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Hank & his clone Circus Hank explain the power of epigenetics, which studies the factors that determine how much or whether some genes are expressed in your body. Like SciShow on Facebook! http://www.facebook.com/scishow Follow SciShow on Twitter! http://www.twitter.com/scishow More SciShow! Solar Energy - http://youtu.be/4uPVZUTLAvA Foldit Gamers FTW - http://youtu.be/JdBcpdH_ptA
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Text Comments (4605)
Nassem (2 days ago)
Epigenetics: the study that everything that grows has humble beginnings. Your life is made of the decisions you make; what you've yet to do or doing right now determine your success, however success isn't guaranteed.
Gwendolyn Lewis (3 days ago)
This is so cool, I thought of this but couldn't put it into scientific terms.
PAULA LIGHTSEY (3 days ago)
Simply said, you can change when you become aware and when you desire change. Being aware and understanding your experiences and environment can usher you to different outcomes.
Braedon Mitchell (5 days ago)
Someone tell this guy he isn't John Green
TheCitedAviator (6 days ago)
6 years ago god Im so glad you dumped the beard
carlos glenn (8 days ago)
WoW!!! This explains sooo much! And though ground breaking, soooo simple and predictable.
Callie (11 days ago)
watching this vid was actually assigned to me in bio class lol, best assignment ever..
Therese Jackson (14 days ago)
I think about my slave ancestors who had poor diets and distress.
CerberaOdollam (16 days ago)
Yeah, childfree here, so whatevs.
Pimm the Giant (17 days ago)
Epigenetic cookies!
Julio Ulloa (18 days ago)
2012 hank were allways drunk?
luciferangelica (19 days ago)
you don't know what to do with it
luciferangelica (19 days ago)
you: don't know what. to do! with it?
luciferangelica (19 days ago)
ham is gross and hot pockets are made by the lowest of swine
luciferangelica (19 days ago)
you're a sword swallower and bearded lady
acleansweep (19 days ago)
8:30, yes it's incredibly bigoted and ridiculous to suspect that more intelligent people might somehow be more successful at acquiring and keeping resources and therefore produce stratification along lines of intelligence. But intelligence testing is valid, IQ is vastly more influenced by genes than anything else, and genes are obviously heritable so...? The truth is bigoted I guess?
Lightcruz17 (22 days ago)
We can sit out in nature (barefoot) and manifest our reality by asking Mother Nature so help us heal 💜
TTK 27 (23 days ago)
I disagreed at 6:00 mark.. I believe disease was created.. all the injections we now receive after we’re born proves that..
Brian Notapplicable (23 days ago)
Humans are creatures of habit.
lf 01 (26 days ago)
This could be the breakthrough that we need
Andy Scott (30 days ago)
Don't give millennial and SFW anything else to be oppressed by FFS! Blaming grandma LOL!!!!!!
James Hally (1 month ago)
This has a massive impact on Darwin's evolution model
Damon Albarn (1 month ago)
So basically, we all might be quite infinitive variations of ourselves. We can be "good" or "bad" variation based on our choices and the things around we are expose to.
Niv Woolley (1 month ago)
It's tattoo. 😊
ninth Chakra (1 month ago)
*Epigenetics* has enormous potential in completely preventing genetic diseases (including some cancers) from passing through to the next generation, making it incredibly important to every one of the billions of people alive today. There's also the ethically murkier use of Epigenetics to "improve" the human species (according to concepts discussed by Transhumanists). Ideas like: extending lifespan, delaying senescence, even augmenting intellect, which (with technologies like CRISPR Cas9) may actually be achieveable during current human lifetimes. ~ ~ ~ On a related note, one of the greatest evolutionary biologists that predated Darwin was *Jean-Baptiste Pierre Antoine de Monet, Chevalier de Lamarck* . Given the new evidence that we're learning about Epigenetics, I think that you should definitely devote a future episode (or even series) on his theories, commonly called *Lamarkism* , as many biologists are revisiting aspects of his ideas that were thought to have been made obsolete by Darwin's theory of evolution through natural selection.
Time To Thrive (1 month ago)
Is it ironic that when you did that impression you sounded like Homer Simpson?
Ionic-Android (1 month ago)
The beard looks awesome
Dave McKay (1 month ago)
i think whole memories of someone's life is contained in our DNA, couple with that of a shared experience of the the other side of our our self, thus we have biological symmetry.
A bowl of salad (1 month ago)
So before I have a kid, I’ll do calculus, become fit, and become an artist.
Velma Velvet (1 month ago)
So would it be better to have children younger since you probably won't have as much genetic baggage?
H2N (1 month ago)
Nobody, but nobody seem to expalin this: If a gene is turned off, what the hell is expressed in it's place? If i have, let's say, a mutated finger, and i cover that gene up, there would be no finger expressed? What would it be insead of that mutation? It can't be nothing, please, explain this to me, i would apreciate it very much!
H2N (1 month ago)
Hello! Our last conversation left me think about this: if a gene is bad, in the perspective of epigenetics, what exactly makes the helicase go and read the "backup" copy in another part of the genome? How does it know that a speciffic gene is the right one if it's not in the range? Thank you!
Pootis Spencer Here (1 month ago)
You too!
H2N (1 month ago)
Great! I sure am. i'll leave you a comment here. Have a nice day (or evening)! and thanks again!
Pootis Spencer Here (1 month ago)
Oh, please do, I love to teach people who are interested in learning!
H2N (1 month ago)
I might contact you in the future for an advice or two, if you'll have the time and mood... i promise i won't be buggy :))
川田ユキオ (1 month ago)
Sorry sons and grandsons. Ive already made a lot of wrong choices. Counting on you to fix it.
Andrea Lewis (1 month ago)
Excellent excellent video! Very inspirational! Thank you for making it!
Lulu A (1 month ago)
thank you..that was brilliant!!
Dave F (1 month ago)
William Love (2 months ago)
How do a person change the genes of their hair or scalp to grow hair that is easy to manage?
David Urban (2 months ago)
5:00: isn't it a huge effect that affects your life instead of a huge affect?
David Asher (2 months ago)
Did the movie Trading Places with Dan Akroyd and Eddie Murphy come into anyones mind? While the changes in the subjects were greatly accelerated, the more I watched Hanks video the more I thought that movie applied.
Deprived Dolphin (2 months ago)
So essentially, what we thought was simply observing our parents making poor choices that determines bad behavior, is actually a Darwinian type of genetic passing from parent to child? But it can change based on a child’s own personal life experiences...
Her Melanin (2 months ago)
This is too unscientific......
sonya johnson (2 months ago)
So helpful, thanks so much!
Vgpl0 (2 months ago)
You seem to have forgotten that it's the person who's alive that has majority control over the expression of their epigenetic info, not the person that's dead. You're leaving out a huge part of the field and leading these people to believe they're still victims, when in reality you couldn't be any further from the truth. It's people's environment/their perceptions that affect their epigenetic expression predominately, not their parents'/ancestor's experiences, those snippets of information serve as a baseline of operation, not as the end-all-be-all. You're treating epigenetics like they're genetics AKA inherited "actions and reactions" from one's parents, and that's completely wrong. Do yourself a favor and stop spreading misinformation.
David Robert Gibson (3 months ago)
Horrible delivery.
John K Lindgren (3 months ago)
6:33 *”Fördelen med glesbygd är att de ee glest med folk” Swedish Lapland. Bangkok-Jomppa CarSanook Media THAILAND*
be bo (3 months ago)
Is epigenetic and organ differentiation the same?
Brianna Zealand (3 months ago)
I hope enough people would be interested in having more videos on epigenetics! It is one of my favorite science topics !!!
Huso3000 (3 months ago)
If you put the video on 0.75% for speed, you sound like very intelligent drunk <3
Justin Harden (3 months ago)
Spelled "Tattoo" wrong. In the DNA, double helix diagram.
Jack Kelly (3 months ago)
This guy has saved my Biology marks so many times!
Nikki Boyce (3 months ago)
If you look up “Smart Little Lena Clones” you can see what this is in real life. The AQHA stallion Smart Little Lena was cloned and his clones are not exactly like the original. Even their markings vary.
Vivek Subramanian (3 months ago)
Fantastic video! Lost it at 4:09 - "we're gonna have to pass something the size of like a Merriam-Webster dictionary"!
Paolo Nardi (3 months ago)
This essentially explains why racism is still such a big problem in our society
Ian H (3 months ago)
- People do not divine what is adaptive for them or their genes; their genes give them thoughts and feelings that were adaptive in the environment in which the genes were selected.
Chris Farrell (3 months ago)
A better metaphor than equating the epigenome to hardware would be that the epigenome is the operating system and the genome is the uploaded software.
T J (3 months ago)
that analogy was so confusing for me
sirsnow (3 months ago)
Genetics? No, I'm way epigenetics.
Jamie Mattinson (3 months ago)
The sad reality of epigenetics is that we are completely, now, genetically inferior to the superhumans that once lived in Africa, specifically prior to agriculture. We'll never, without the help of nanotechnology and stuff, be as athletic and homeostatic as they probably were (aside from maybe disease factors, but not chronic or stress related disease). We've blown it, at least in the 'developed world'. The happy reality, though, is that we can understand epigenetics and use it to give future generations and perhaps ourselves this generation a better shot at homeostasis, health and happiness by altering our behaviours and environment to make ourselves as happy, healthy and homeostatic as possible, and try to work back up to a genetically better-off human race.
B Mc (3 months ago)
Glad you shaved the mustache, Hank. The goatee looks good on you though.
Zenny Abanales (3 months ago)
Meh I don't do stupid unhealthy things anyway but it's not like having good epigenetics is going to stop my children from inheriting my ugly face.
Zenny Abanales (3 months ago)
Omgaaa! Hank's goatee!
Joe Retail (4 months ago)
Glad I found this, Apabetalone is an epigenetic drug that is in a phase III trial right now, FDA and EMA approved....the trial is attempting to prove that Apabetalone, aka RVX-208, that it can substantially reduce the risk of a Major Adverse Cardiac Event like stroke or heart attack, in patients with Diabetes Mellitus, and there's a couple subset populations for Chronic Kidney Disease and Alzheimers. Exciting stuff.....using epigenetics to regulate dna from disease to non-diseased states....hope it works, results due out at the end of the year.
Abel Dean (4 months ago)
Epigenetics does not bypass the hereditarian theory of intelligence. On the contrary, epigenetics entrenches hereditarian theory. That's because epigenetics is 100% all about genetics. The most you can do with epigenetic ideas is hope that the genetic expressions for stupidity are temporary.
Tony M (4 months ago)
Study or your kids will be morons.
Dream Scott (4 months ago)
So like what about the slaves would that trauma cause changes in the epigenome and pass down to the descendants of the slaves
michael rhodes (4 months ago)
Shout out "dear white people" on Netflix thanks Sam
Aaron James (4 months ago)
still i think the bible wrote the first to Sweden on that
Aaron James (4 months ago)
Tight! Brilliant! Science is Life and Jesus Christ is the Lord! This was an excellent first wif of the topic!
Peter never (4 months ago)
Well done. Its hard to find such an explicit definition of epigenetics. You are an excellent guide to greater undetstanding of this puzzling world!
Apodis (4 months ago)
Great video, very interesting. Just to add, I worked in 2 traveling circuses over 6 years. The people there generally work very hard and have to be very fit. They also eat well, and definitely don't have facial tattoos. I found it a very positive and creative environment. I get the point you were making, but the stereotype of circus people isn't true on the whole. I only mention this because they do suffer prejudice based on these stereotypes.
Hessella (4 months ago)
I had (possibly) a great great grandfather who liked tobogganing and did it professionally. I grew up not knowing about him and I loved watching tobogganing on the TV. I think I inherited his wish for the adrenaline rush. Anyway, garlic, turmeric and apple cider vinegar, that's all you need, don;t smoke, don;t drink, exercise, walk, oxygen (according to Paul Davies Physics of Cancer) cancer hates oxygen. oh and watch some Brett Rogers videos. You're welcome. Good vid.
suraj tiwari (4 months ago)
Hope you didn't had any alchohol.
agun17 (5 months ago)
My kids gonna inherit the mems of production.
Diego Fernandez (5 months ago)
Do you have the articles of how epigenetics is heredetary? I love your channel, but I haven't found that information and I don't believe its rigth :/
firepiplup (5 months ago)
face tatoo
Vlogwaves (5 months ago)
8:22 Key counterargument: Michael Faraday. :)
brandon castro (5 months ago)
I'd love to see how life started to where it is now... I'm curious to know the origins of camouflage and vision
Dash the Kid (5 months ago)
Oh "great news!" they have drugs to fix this! smh
Thomas Burns (5 months ago)
Identical twins have many interesting. You would be surprised. If you separated the twins for 50 years you might find they have similar passwords and hobbies and look very similar. They think very similarly.
Eleeth Tahgra (5 months ago)
Ah, its the difference between "Eat, Granpa." And "Eat Grandpa."
Ali Heidary (5 months ago)
thank you
Brian Cortez (5 months ago)
Who else is here because of Transparent?
Phước Phạm Hữu (5 months ago)
oh well now life just sucks more THANK YOU MOTHER NATURE !!!!
kay scott (6 months ago)
How does a face tattoo affect epigenetics?
Chuck T (6 months ago)
Well considering how we eat nowadays vs 50 years ago. How stressful daily life can be. Yea...next 50 years should be interesting
Epigenetics sounds like the lottery of genetics inheritance.
RIchard Healey (6 months ago)
This looks like an episode of a drunk history
young savage (6 months ago)
Lauren Brickett (6 months ago)
You are incredible - and you save my life all the time with tough topics, wish more of my professors could be like you! Thank you!
Lyndley Hillebrand (6 months ago)
I have anemia, anything i can do to help my red blood cells?
Jason Travis (6 months ago)
there is no law that says we have to have two different color genes we can fix/cure inherited traits Stop the hate science only cares about inherited traits, the cure exist dominant and recessive traits, Rise Against said it was "the good left undone" there is a lot of good in everyone, so don't be blinded by there color just hang out and love one another
Charlie Lord (6 months ago)
*trips over tiny clone* ooooooooooopppssssssssssssssssss...
Brittany Pryce (6 months ago)
I love these videos. I'm a substance abuse counselor and psychotherapist - I show your videos all the time to my client groups to explain complex issues linked to mental health and substance use issues. Thank you for making these videos. Greatly appreciated.
john bordes (6 months ago)
Epigenetic and abc
Dayon Mage (7 months ago)
Another example; John and Hank are both brothers with similar genetic material, yet Hank isn't nearly as obnoxiously neurotic or spastic as his sibling counterpart.
I G (7 months ago)
Do genes influene behaviour such as solitary behaviour in cats? If so, how?
ryanjannakhuang (7 months ago)
Why is that 2d globe a Mercator projection
Sam (7 months ago)
Reasons not to have children: To save the environment and to be able to do things without guilt.
eshwar bn (7 months ago)
Excellent topic,fantastically presented, 👌🏻
Elizabeth Shaw (7 months ago)
I wonder after half a lifetime with a genetic disorder where my insulin receptors do not function. If my insulin receptors were suddenly turned on what would happen to me? They kept telling me in 5 years did be able to fix it well I think we're at a point now where it may be able to be fixed but my original team doesn't want anything to do with me because I mentioned money once! They made a lot of money off me and all I asked for was my travel expenses from Maine to Boston and back and my doctor up here at the time and said they would give me that but they never did. It doesn't matter now that was in the 90s and they should be speaking to me now or at least my Dr.
yawning here (7 months ago)
I love how you gave the epigenomes voices (I think I butchered the spelling)
Lilia Lotus (7 months ago)
This lends credence to the idea that people are largely a product of their environment. It also kind of has some horrible implications for people that grow up in abusive situations. And all the children growing up in war zones. What kind of epigenetic changes would occur in populations who have multiple generations suffering through similarly extreme situations of stress?

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