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The Science of Lewy Body Dementia

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This week in SciShow News we dissect what a Lewy Body is and what they are capable of doing. Hosted by: Hank Green ---------- Dooblydoo thanks go to the following Patreon supporters -- we couldn't make SciShow without them! Shout out to Justin Ove, David Campos, Chris Peters, Philippe von Bergen, Lilly Grainger, Happy Birthday!!, Fatima Iqbal, and Justin Lentz. ---------- Like SciShow? Want to help support us, and also get things to put on your walls, cover your torso and hold your liquids? Check out our awesome products over at DFTBA Records: http://dftba.com/scishow Or help support us by becoming our patron on Patreon: https://www.patreon.com/scishow ---------- Looking for SciShow elsewhere on the internet? Facebook: http://www.facebook.com/scishow Twitter: http://www.twitter.com/scishow Tumblr: http://scishow.tumblr.com Instagram: http://instagram.com/thescishow Sources: https://theconversation.com/robin-williams-had-dementia-with-lewy-bodies-so-what-is-it-and-why-has-it-been-eclipsed-by-alzheimers-50221 http://www.lbda.org/content/lbda-clarifies-autopsy-report-comedian-robin-williams http://www.lbda.org/content/lewy-who http://www.parkinson.org/understanding-parkinsons/what-is-parkinsons http://www.ihcworld.com/_protocols/general_ICC/staining.htm http://ghr.nlm.nih.gov/gene/SNCA http://www.ncbi.nlm.nih.gov/pubmed/12012571
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Text Comments (451)
SHAWN MICHAEL Duncan (24 days ago)
I know somebody diagnosed with this recently.
JUNGO (1 month ago)
another idiotic brainless wonder wanting you to subscribe...……...
TeflonTommy2 (1 month ago)
My brother got diagnosed with Parkinson's at age 29. He's 40 now and just got diagnosed with dementia a few months ago. He's been dealing with hallucinations for years now. Sadly it's probably Lewy body. It's heartbreaking to watch him rapidly go downhill.
MrBobberino01 (2 months ago)
Please discuss frontotemporal dementia. FTD
Saddle Ridge (2 months ago)
Good report but for heaven's sakes , slow down the machine gun rapid fire delivery.... please.
Shea Goff (3 months ago)
My papa has Lewy body and it’s hell for him. He hallucinates constantly and has trouble with everything. It really kills me to see him slowly going down hill like he is.
Ladan Mahgoub (3 months ago)
The second most common cause of dementia is vascular disease not Lewy body
Sinbio Monet (3 months ago)
Well done.
auroraborealis X (5 months ago)
Did He had bipolar disorder.
Average Misfit (5 months ago)
I didn’t even know he had that
Celeste Marron (5 months ago)
Slow down... your giving me Lowy body dimentia.
ZoophreemiaHouse (8 months ago)
Why did u have to report this 😓
ZoophreemiaHouse (8 months ago)
Antipsychotic medication exasperate the problems of psychotics/psychosis over time thy r only good for short time use form the symptoms of these disorders. Stop book reading ur life and experiences the world, get to know ur self and the world not solely on other peoples writing of it.
Lonnie Howard (9 months ago)
This is a superb memory loss treatment solution “shocking cuno press” (Google it)! I have been using it several weeks now and feel my memory and response time has enhanced. I`ve got dyslexia and has helped me with tasks I do everyday at work and home. Great for working your brain and keeping it active. Utilizing this is exciting..
Jason McCann (9 months ago)
The fight against the microscopic manifestations which cause macroscopic symptoms is the saddest war we have ever fought, and it goes on and on. Goodbye again, Robin. :'(
Aw Spartan (10 months ago)
My grandfather passed away from this disease,and its been 18years and i still miss him.Robin Williams is my favorite comedian and I miss him also.
TheTonyShowShow (11 months ago)
I was wondering if he was sick and having psychological problems would he still go to hell since he killed himself?
Saddle Ridge (2 months ago)
TheTonyShowShow. I do not know if Robin Williams knew Jesus Christ as his Lord and Savior. If he did, he is not in hell. It's Catholic teachings that say suicides go to hell. It's not biblical.
George Eaton (11 months ago)
I read that the second most common type of dementia is Vascular dementia which can occur after the blood supply to the brain is interrupted due to events such as strokes. Is this right?
marc bell (1 year ago)
I am guessing that there has never been a treatment for any disease caused by mis-folded proteins. Am I correct?
JNK (1 year ago)
You speak far too fast for people with no dementia.
Darrin8112 (1 year ago)
Robin isn't dead its all part of his new stand up come on people you really think he is dead? He will come back in a few years and say i got you all the planets biggest practical joke 😂
Illuminati_watching (1 year ago)
A resident at the rehabilitation center I work at has Lewy body dementia and is just the sweetest guy.
evelyn273 (1 year ago)
does this mean that Lewy body dementia cannot be detected/diagnosed until an autopsy upon death?
Brayden (1 year ago)
evelyn273 A diagnosis can be made with some degree of certainty but it can't be 100% confirmed without autopsy. As in examining brain tissue under a microscope. Hard to do on someone whos still alive...
Socratease 1 (1 year ago)
Slow down! Your approach is like a quoted dictionary and, by a never ending persistence, negating the natural urge of young and older people from attempting to learn about the subject. ,
Corn W (1 year ago)
My husband was diagnosed with Lewy Body Dementia 4 months ago, his health have been going downhill very quickly. :-(
PeachesforMe (1 year ago)
So does SR Foxly Own Scishow about now?
Ms3queen (1 year ago)
RIP Robin. We miss u!
Sheri Dildar (1 year ago)
Hank Green! Crash course misses you. 😊😊😊
Victoria Famoriyo (1 year ago)
Robin was the best in the Bicentennial Man 😭😭😭 so sad he's gone.
Melanie Sperling (1 year ago)
I would like to show this to a group but the presenter is speaking too fast.
Cat (1 year ago)
check out Mollys Movement right here at YouTube, a son is filming his mother's Lewy body dementia, it's heartbreaking, spirit lifting and all done to bring awareness to this disease.
Ella Sawal (1 year ago)
Hey I'm doing a project about lewy body dementia and I was wondering if you can tell me what body system is affected by Lewy body dementia and how
gokucrazy22 (1 year ago)
so the video didnt go over this, but alpha-synuclein is also a big part of alzheimer's!
Salina Neuman (1 year ago)
This video was wildly accurate. I appreciate that!
Yeh Kasee (1 year ago)
Slow the hell down!
akshooter762 (1 year ago)
man I been drinking, and I been smoking.... slow the fuck down! well I guess I could put you on .5 speed bahahaha so funny... he sounds high as a kite.
Manu Das (1 year ago)
vascular dementia is the second most common cause of dementia after alzheimers..dumbass
Dax Bourcier (1 year ago)
Lewy body dementia is the second most common *in elderly patients*. Vascular dementia is the second most common. Great video.
Venice Mackay (1 year ago)
are the changes in the genome from epigenetic changes or in the main DNA ie not a tag that could be switched off with medication as is being studied for other illness such as cancer.
piasauevey (1 year ago)
Not to be 'that guy' but it's the 3rd most common, after alzheimer's and then vascular dementia :)
bob b (1 year ago)
I thought the title said lewd body dementia.
Venice Mackay (1 year ago)
Scarlet Red (1 year ago)
a horrible disease so frightening for the person my mom is quickly declining and it's just awful executive functions gone in the snap of a finger, mood swings if you can call it that night and day lost ability to walk without assistance , fits if fright then swings to aggressiveness completely powerless to help awful awful disease
62636263c (1 year ago)
As it turns out, Robin was suffering from all of those symptoms. His Wife just released an essay about Robin's last days, and she listed every one of them. Shame they couldn't have figured it out earlier. At least then, he could have had some understanding as to what was causing his problems, and maybe come to terms with it. Possibly even work to raise awareness of it's existence.
Emilie Masi (2 years ago)
Great video, thank you. However, you mentioned Lewy Body dementia is hard to treat as people are sensitive to anti psychotic medication. It is recommended anti psychotics are avoided when a diagnosis of Lewy Body dementia is made. Recommended pharmacological treatment includes cholinesterase inhibitors, which assist in reducing agitation, reducing psychotic symptoms and cognitive impairment.
ECW Platinum (2 years ago)
Watching this cause my grandpa has this. Too bad there's no treatment or cure :/
Dauf (1 year ago)
ECW Platinum sorry to hear that man
apiece ofdirt (2 years ago)
It's sad that the death of a famous person put LBD in the spotlight because it's not a new disease. My father passed away from it in 2013 after a 5 year battle quietly at home with his family. Williams death was not peaceful. A hanging is a violent way to die and I feel sorry for his kids having to live with what he did but I'm sure they put on a brave face of understanding. We as a society make these "stars" seem godlike and we put them on a pedestal and forget that they are human.
Wiggins (2 years ago)
RIP RW. Legend.
Patricia Santovasi (2 years ago)
Excellent presentation. Clear, concise and well spoken. Explains it well and accurately. My mom was diagnosed with Lewy Body Dementia. She too had all the symptoms described here. She lived with my family, with her disease, for 8 years, slowly getting worse and worse. The hallucinations were demonic and horrific. She is finally at peace. This is one evil disease...........
Jenasta (2 years ago)
Thanks for making this. My dad had Lewy Body dementia and died in the late 90s when I was 18. There was so little information around then and it was hard understanding what was going on. I know many of the symptoms and drug side effects were terrifying for him. I've just shown this to my 75yr old mother and she's so happy to see more awareness of it and to get more of an understanding of what went on.
Jenny Heubeck (2 years ago)
this is really helpful, my granny has been diagnosed with this recently.
valcarni1 (2 years ago)
Future president of space: Donald Trump
B Mc (2 years ago)
I would be interested in watching you talk about happiness and seriton
Suzie Park (2 years ago)
Miranda Bella (2 years ago)
The worst things always happen to the best people
Julie R (2 years ago)
Good info, but spoke WAY TOO FAST. Overwhelming.
Malisa Hayes (2 years ago)
Many people forget that Estelle Getty also had and died from Lewy Body Dementia as well.
Mallory Wilkins (2 years ago)
This is a great overview, but you talk so fast it's hard to take it all in.
Joseph Ayorinde (2 years ago)
My grand mother just died from Alzheimer's this past summer. I know this is slightly off topic.
Nastrael Rowe (2 years ago)
I'm sorry, but I can't stop imagining having to perform an autopsy on Robin Williams. If I had to do it I'd probably have a mental breakdown.
Jenni Doughty (2 years ago)
slow the fuck down!!!
scotthouse100 (2 years ago)
Good info, usually I like the comments parts of these stories better than the stories but I'd really like to know how to find out more about this. Thanks.
Emily Johnson (2 years ago)
The fact that dementia is diagnosed when it is already to late is of course an error that we are still trying to figure out. Most times it is diagnosed after death. Technology is slow in the advancement of figuring out dementia and early treatable diagnosis. I don't think I will see it in my lifetime at least....When dealing with such a difficult disease it brings up a lot of ethical considerations. For one, having a good relationship with a doctor over a period of time develops a relationship. This can help so that the doctor can look for any changes in the patient. Of course, by the time any symptom shows it is already too late. If we are going to cute this disease we need to do so before any symptoms show up! Anyways, the doctor may catch the early warning signs of dementia and start treatment early to further delay any advancements.
Emily Johnson (2 years ago)
+Sidd Well for one, the doctors better be looking out for their patients and detect accurately early. I know there could be malpractice issues involved for the sake of the doctor in diagnosing. I know misdiagnosing will be common in the beginning and all throughout the process. It still occurs daily for so many people. Also, medication prices for treating the disease may be of ethical relevance. If prices are higher just so the companies that provide them can earn more, some americans without insurance won't have access. I only say this because it is the case for many people today for any ailment.
Sidd (2 years ago)
+Emily Johnson What type of ethical dilemmas do you mean?
Emily Johnson (2 years ago)
+Sidd I had learned this in both my neurpsyc class and Healthcare ethics class. In relation to advancement, yeah I do agree that we have come so far. I know that there will be ethical dilemmas that follow this advancement once we find a cure.
Sidd (2 years ago)
+Emily Johnson Where did you get this information from? It is true that technology is a bit slow in advancement but it is also very far ahead. Just think, we can already identify many types of dementias.
Voices From Me (2 years ago)
I still think Robin Williams was murdered. His wife's alibi wasn't very put together. Even if he was hallucinating, that wouldn't explain how he was able to hang himself. And why would you cremated the body? Love you SciShow, keep up the great work!
kolus kor (2 years ago)
is it me or this explanation makes it even harder to understand!??!
jackdawcaw (2 years ago)
+placide chris it's you.
TheRogueMage (2 years ago)
s4ujcd (2 years ago)
I feel sorry for Robin Williams, but if fate had that in store for me, I'd off myself too.
Hannah Shoshana (2 years ago)
So, are Lewy Bodies somewhat like non-infectious prions?
Britani Bryant (2 years ago)
You all should do a video about suicide. Although a somewhat depressing subject, it would be interesting to see why or how the brain can talk oneself into thinking that self-destruction is the way to go...or something less depressing like self-destructive plants or insects.
Debbie Miller (2 years ago)
I wish people would just comment on the topic of the video instead of jumping into thermonuclear war and politics. Nothing like comments from the peanut gallery.
Debbie Miller (2 years ago)
The most recent interview with his widow has her telling how Robin misjudged the steps to the bathroom. He fell, hit his head, blood everywhere. He told her he had misjudged how far away the door was.
Pega Broster (2 years ago)
You should do an episode about Thorium and it's use as a potential replacement to Uranium as nuclear energy.
Wilfrid Somogyi (2 years ago)
The 90s were a quarter of a century ago.
Martin Vargic (2 years ago)
What is the purpose of humanity?
marc bell (1 year ago)
boomstick900 (2 years ago)
+Martin Vargic To either save or destroy this planet. To either progagate throughout the universe or die off. Who's to say really.
Hannah Brooks (2 years ago)
My grandpa had Lewy Body Dementia but it was diagnosed as Parkinson's. The doctors told him that his hallucinations were a side effect from taking so many medications.
joelproko (2 years ago)
Patch Adams/Mrs. Doubtfire/Prof. Brainard is dead?!? T_T
thecognacsipper (2 years ago)
1968DodgePolara (2 years ago)
Very Bad illness to have. Watching my Dad slowly go down hill the past 3 years was a nightmare taking his life at the end this past April. RIP Father :(
Olivia Isleman (2 years ago)
Thank you so much for shedding some awareness on this. My grandmother suffers from this and it gives me a little reassurance to know more about it and know this may reach others with more means than myself to find a cure. My grandma will be 70 this March and until 8 months ago she lived by herself and could drive, she suddenly started having severe hallucinations and had to be moved to an assisted care home and can't walk or feed herself. It's a terrible thing for a person to have to go through and it's scary to know that even the strongest people you know can be brought down by small biological malfunctions. I hope this spreads like a virus
jhosioja (2 years ago)
My grandfather had it, and it was terrible. He was in top physical condition prior to it, so he stayed alive for over a decade after the symptoms started, but like many people with relatives with Alzheimer's know, it's tough to see that sharp, funny and creative person turn in to a shell who barely knows his children, has trouble with his first language and needs help to go to the bathroom.
SHIFTKICK (2 years ago)
Hallucinations can occur in advanced stages of PD, I recently read a research article on trying to locate the source of dysfunction in the brain. Unless those patients were wrongly diagnosed and really suffer from Lewy body dementia?
Saddle Ridge (2 months ago)
My Mom had Parkinson's and she started 'seeing ' people who weren't there. Also , hearing conversations with people's names in it that she knew, but the people talking did not know. ( Example, nurses in hospice are having a conversation and she hears her granddaughters named over and over) Maybe she actually had Lewy Body too? Doctor's 'try' all kinds of medications on people to 'try' to help but the fact is, each individual will react to medications in a different way and sometimes those medications actually exacerbate their problems.
Andrewsarcus (2 years ago)
talking about degenerative disease, have a look at pictures for peripheral vascular disease.
Andrewsarcus (2 years ago)
pk47i (2 years ago)
Please cover tensor flow aka secret sauce(of google).
lee oi leng (2 years ago)
Tyler Hamilton (2 years ago)
this is something I'm tinkering with in my free time but why have we not come up with a inexpensive solar cooking system that could be mass produced for the millions of starving people in the world people are using dangerous harmful methods to prepare food thought if anyone might have an idea it would be this community DFTBA
SoloFaerie (2 years ago)
I'm curious if Lewy bodies(?) can be found with other dementias? Meaning can you have Lewy Body dementia, as well as another type...basically, while the family had agreed to donate my dad's brain, to dementia research, when he died, my mom changed her mind, and I'm wondering about symptoms my father displayed.
Chief Shitlord (2 years ago)
I have a legitimate question: why do cats seem to be terrified of cucumbers?
Saddle Ridge (2 months ago)
cucumbers resemble snakes to a cat
MsLazyllama101 (2 years ago)
Lewy Body is an awful disease- I watched my grandfather suffer through it for several years before he passed away.
modernoverdrive (2 years ago)
I did not know Robin Williams had this. I know Casey Kasem had it.
Clock Man (2 years ago)
Lucky day for scishow with 777 videos
Adam Thornton (2 years ago)
I have to idea who SR Foxley is, but I'm becoming a fan!
Rad Bromance (2 years ago)
Being forced to pay his ex-wives alimony (welfare payments) probably didn't help with his depression either.
zolacnomiko (2 years ago)
Thank you SciShow for bringing awareness to this disease. I know it only because I know someone with this diagnosis. It's a horrible disease, rough on him and his family. Here's hoping for a cure someday!
Wade Haden (2 years ago)
what hallucinations do they experience?????
Taber McFarlin (2 years ago)
This is so strange, I just lost my grandmother to Lewy Body dementia this past week.
MPythonGirl (2 years ago)
So, I have a question and I don't know where to post it. Since Scishow is the kinda miscellaneous channel partnered with more specific ones, but there isn't an official way to ask questions, I'll post it here (currently the most recent video). If anyone can direct this to the appropriate place to ask this, that would be awesome. The Estrous Cycle: what's up with that? And why do dogs bleed if they aren't menstruating? I've looked into it, and as far as I can tell the stuff we lose while menstruating is reabsorbed in estrous species. Dogs and cattle bleed at the beginning of heat... apparently as a side effect with no use? Like, the blood just rushes to genitals so much the veins leak? Why?
Just out of curiosity, if it were possible to somehow remove the Lewy Bodies without touching anything else(say like with a transporter from Star Trek), would that reduce the symptoms?
Audrey B (2 years ago)
SciShow staff, I think your work might help my family. My grand-ma has been diagnosed several years ago with PD and depression, and for a year or so she has slided into full dementia that doctors put on the account of old age. Except that what she has is full on what you are describing here. I've looked at specialized websites, and it does sound like she has been misdiagnosed from starters :/ I just notified my mother of this possibility, and she said she will read what I have found, but she doesn't know how to say to doctors that they might have been wrong :/ Anyway, even if it turns out it's not what she has, I want to thank you for talking about this, and raising awareness about illnesses.
Le Paca (2 years ago)
lewy, lewy, lewy, lewy... lewy, lewy, lewy, lewa... Sry :)
PatrickAllenNL (2 years ago)
Let's rename that disease to Robin Williams dementia
Shwat Toddle (2 years ago)
AKA he killed himself over the wrong thing. I bet he feels really....oh never mind.

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