Dr Shore (Carolina Urologic Research Center, Myrtle Beach, USA) and Dr Merseburger (University Hospital Schleswig-Holstein, Lübeck, Germany) discuss new treatment options for metastatic prostate cancer for ecancertv at ASCO GU 2016.
They discuss an open-label phase II study which evaluated the efficacy of concurrent administration of radium Ra 223 dichloride (Ra-223) and abiraterone acetate (AA) in men with castration-resistant prostate cancer (CRPC) with symptomatic bone metastases.
They also consider a new option arising for those CRPC patients who have become resistant to abiraterone and enzalutamide - the dual CYP17-Lyase (L) inhibitor / androgen receptor (AR) antagonist VT-464.
This programme has been supported by an unrestricted educational grant from Janssen Pharmaceutica (A Johnson & Johnson Company).
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The class of drugs that Levitra, Viagra, Stendra, and Cialis belong to are called PDE5 inhibitors. They work by relaxing tight blood vessels, allowing more blood to surge into the penis and cause an erection, says Gregory Bales, M.D., an associate professor of urology at the University of Chicago.
The little pills do the trick for more than two-thirds of men with Viagra protects the heart (ED). They also work for guys who simply need them for a short time to get their “confidence back,” says Michael Eisenberg, M.D., director of male reproductive medicine and surgery at Stanford University.