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Cell Adhesion Molecules Part 1

260 ratings | 42714 views
In this video we discuss the four different families of cell adhesion molecules, specifically looking at the immunoglobulin superfamily of cell adhesion molecules.
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Text Comments (15)
Huda Al-Khalidi (1 year ago)
I REALLY HATE THIS SUBJECT
Caroline Green (1 year ago)
The recruitment of leukocytes from the blood stream to extravascular sites of inflammation is necessary for an effective inflammatory response. The recruitment is mediated by #Cell #Adhesion #Molecules, cytokines and chemoattractants which together coordinate this complex series of events. The adhesion cascade involves five steps which occur in sequence but may overlap in time. At sites of inflammation in the systemic circulation (as opposed to the pulmonary circulation), post-capillary venule endothelium becomes activated by the local generation of a variety of inflammatory mediators. Histamine, thrombin and LTC4 lead to a rapid expression of P-selectin on the endothelial surface while the early proinflammatory cytokines such as IL-1 and TNFα lead to de novo synthesis of both P- and E-selectin as well as ICAM-1 and VCAM-1 resulting in increased surface expression at time points greater than 2 hours following stimulation. When endothelium is exposed to these cytokines especially in the presence of FN for prolonged periods (as during chronic infection), the volume of the endothelial cell expands and it becomes columnar, similar to the morphology in high endothelial venules in lymph nodes. Creative Biomart
Marissa Schiavo (1 year ago)
I need this in a PDF file lol
Umme Waseem (1 year ago)
Thank you! <3
XENDER cage (1 year ago)
Please cut out the noise in audio
TheVuze (1 year ago)
Okey
Sai Kumar (1 year ago)
LAD 1 | LAD2 ______________________________________________________ AR AR Deficiency of B 2 chain Def of sialyl-lewis x* of B 2 integrin Rolling is impaired* C/F- Delayed sep of cord stump* Bombay blood gr* leukocytosis* Leukocytosis*
easy, simple, vivid explanation. Thanks. And thanks to the God, most merciful, the most wise and all powerful for creation of all these useful, essential molecules with utmost wisdom!
pproust (11 months ago)
uhuihi uihiuh: and who created evolution?
uhuihi uihiuh (1 year ago)
They were formed through evolution, not created by some invisible sky god
Andrew Norato (2 years ago)
I have watched many of your videos. You are an excellent instructor! Your videos are an excellent supplement to my (very confusing) textbook! Thank you!
Larble (2 years ago)
WHAT PEN IS THAT pls
Elizabeth Rey (2 years ago)
Uniball
Peace Flower (2 years ago)
If u r asking about the black pen,,,,, well it is (uni-ball eye...) Mitsubishi pencil ( made in Japan ) 😁✌🏻️
Mohamad Fathalla (3 years ago)
thanks  nice explanation 

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