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Ocrelizumab: What to Know About the First Agent Approved for Primary Progressive MS

Оценок: 151 | Просмотров: 12871
In this five-minute video, MS specialist Robert Bermel, MD, distills the essentials about how this new agent works, what makes it unique and what it achieved in pivotal trials.
Категория: Наука и техника
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Текстовые комментарии (16)
Sheridan Rose (20 дней назад)
Had my first 50/50 infusion and now my first full infusion and my second full in May 2019. I didn’t have any side effects at all. I have to leave 5:30 AM drive 200 miles and spend 5 hours in hospital doing the infusion and ten 200 miles back home after infusion. Makes for a real long day. I’ll get my first MRI since starting the process on February 1 2019. I still have balance, fatigue, cog fog issues. Not worse may sometimes a little less. But hey! I’m alive and doing fine!
Melinda Lewis (2 месяца назад)
What are the side effects/untoward effects of this drug?
Melinda Lewis (2 месяца назад)
Also, specifically, how is this drug better than Rituxan?
Olga Mesh (10 месяцев назад)
What is better Tysabri or Ocrevus?
MSHotMess 2010 (5 месяцев назад)
Olga Mesh Big O is supposed to be a much better treatment. And there isn't supposed to be a risk for PML. BUT there have been patients who have developed PML after starting Ocrevus, but they can't pin point if it was caused by the use of prior treatments of Tysabri or Techfidera. Before I started it I did and still have been doing a hell of a lot of research on this and from what all I've found ALL monoclonal antibody targeting treatments carry a risk of PML.
Khaled Hany (1 год назад)
where can I get this presentation PowerPoint??
TulsaGirlForever (1 год назад)
I was diagnosed 1998 w/ numbness that went away. I failed to start therapy. I had my last episode 1999. I started Avonex 2000, Copaxone 2003 & tried Gilenya Jun 2013 for 6 months. Gilenya basically takes the white blood cells & tucks them away into the lymph nodes & the spleen. Not good. As a result, there's not many cells out there fighting foreign bodies. This is not the same process of Copaxone. So somewhere in the Southwest USA between West TX & CA, I contracted Valley Fever, aka Coccidioidomycosis (fungal infection) & had 3 different incidents from Dec 2nd to Jan 12th (UTI, cold w/ fever & a BAD infection in a legion on forehead). Starting Dec 2, I was treated w/ powerful Lanko & other antibiotics, for months! A biopsy was finally done in April on my forehead infection at the request of a family Dr....my brother. My small town Dr's cultured it but got back Clear results. They never even THOT about testing me for fungal or viral infections. Valley Fever is a nasty fungal infection! After getting that diagnosis I stopped Gilenya & went back to Copaxone & have been trouble free since then. whew~ My question is....is there any research or information about complications of treating a person w/ VF, Cocci or a fungal infection w/ Ocrevus?? I'm SO nervous about trying a "new and/or improved MS therapy now,....I want to start using this drug, I'm a prime candidate other than the fact that I contracted Valley Fever.
Cheri Matyjaszek (1 год назад)
Receiving my full treatment on the 8th of November.
Vjekoslav Šket (9 месяцев назад)
Cheri howe is with that new cure, is it better? i have PPMS and europ union approved that medication and i wait till octobar 2018 to take it! Pleas tell me howe is it!?
Amir Ardat (9 месяцев назад)
Cheri Matyjaszek how do you feel now?my wife is looking to go on it.
Danny Boy (1 год назад)
they have left out the side effects -    the brain infection etc that odds do increase over time.
Blood Beryl (7 месяцев назад)
Danny Boy ahh, the dreaded progressive multifocal leukoencephalopathy
Richard Lisacki (1 год назад)
I am 70 years old and was told that the benefits of MS drugs decrease after age 55 and the risks out way the benefits. Studies that are conducted when a drugis approved are done on younger people, 40's and younger. Is this true?
Debra Barton (6 месяцев назад)
I wasn’t diagnosed until I was 50. I believe I had it for almost 20 years before.
JoeD60 (1 год назад)
They are giving it to all ages.
Buddhas Aficionada (1 год назад)
Wow! Thank you Robert Bermel and Cleveland Clinic, that's quite a breakthrough.

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