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Side Effects of Antiarrhythmic Medications (AADs)?
www.GetSMARTAboutAfib.com Medical therapy for the treatment of Atrial Fibrillation has been described by cardiologists as less than optimal. Patients are often alarmed to find that the medications used to maintain sinus rhythm in patients with Atrial Fibrillation are often associated with numerous side effects. If you or a loved one suffers from Atrial Fibrillation don't delay treatment of this progressive disease. Get Smart About Your Treatment Options. www.GetSMARTAboutAfib.com
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sotalol side effects
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Antiarrhythmic Drugs
This is a brief overview of antiarrhythmic agents, or drugs used to resolve abnormal cardiac rhythms. I created this presentation with Google Slides. Image were created or taken from Wikimedia Commons I created this video with the YouTube Video Editor. ADDITIONAL TAGS Class IA antiarrhythmic agent Moderate sodium s, which s action potential duration Quinidine side effects blocks hERG , which results long QT and can cause torsades de pointes Procainamide Less prolongation QT segment, less TdP Disopyramide s force contraction heart Side effects: constipation, urinary retention, glaucoma IB antiarrhythmic Mild sodium s, which s action potential duration Lidocaine Intravenous only Mexiletine Can be administered orally IC antiarrhythmic Marked sodium s, doesn’t change action potential duration Flecainide Possibly produces an ventricular arrhythmias Propafenone Some beta er effects (bradycardia and cardiac inotropy) addition to changing AP duration by changing Na influx, Is also: phase 4 depolarization threshold potential sub degree Na+ AP duration change Beta-adrenergic receptor ers (beta ers) catecholamines (norepinephrine, epinephrine, dopamine) Reduces myocardial need for oxygen, can ischemia slope phase 4 depolarization s self-generated rhythmic firing heart (s automaticity) Prolong repolarization AV node → reentry Effectively s refractory period III antiarrhythmic s potassium s (delayed-rectifier potassium (DRK) s) Prolongs repolarization (phase 3) Amiodarone, Sotalol, Ibutilide, D etilide, Dronedarone III: Amiodarone Wide range effects through many mechanisms s sinus node firing s automaticity s reentrant circuits s Na, K, and Ca s ( I, III, IV antiarrhythmics) s alpha and beta ( II) adrenergic receptors → vasodilation and d intropy Treats many tachyarrhythmias: atrial flutter, atrial fibrillation, vtach, ventricular flutter, SVT Pharmacokinetically unique: absorbed slowly, deposits adipose tissue Half life 25-60 days → cannot easily diminish or reverse effects Side effects: pulmonary (pneumonia, pul fibrosis); cardiac (brady, arrhythmias, long QT, TdP); thyroid (due to iodine); GI; CNS Amiodarone Wide range effects through many mechanisms sinus node firing; s automaticity; s reentrant circuits; Na, K, and Ca alpha and beta adrenergic receptors vasodilation and intropy Treats many tachyarrhythmias: atrial flutter, atrial fibrillation, vtach, ventricular flutter, SVT Pharmacokinetically unique: absorbed slowly, deposits adipose tissue Half life 25-60 days Side effects: pulmonary (pneumonia, pul fibrosis); cardiac (brady, arrhythmias, long QT, TdP); thyroid (due to iodine); GI; CNS High rates torsades de pointes Dronedarone (amiodarone analog without iodine) Gastrointestinal side effects but not TdP Sotalol Calcium L-type Ca2+ Most effective cells dependant on Ca (SA, AV nodes) transmission through AV node (for rapid atrial pulses) Terminates reentrant rhythms Treats AV nodal reentrant tachycardia (primary treatment) Side effects: hypotension and heart failure pts taking beta-ers Diltiazem and Verapamil Digoxin Inhibits activity sodium potassium pump (Na+-K+ ATPase inhibitor) Treats heart failure complicated with atrial fibrillation (by decreasing heart rate) s vagal tone; reduces sympa tic activity Opens potassium (K+ activator) Intravenously with saline flush (short 10 s half life) Hyperpolarizes cells Allows for rapid termination reentrant supraventricular tachycardia chemical defibrillator
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Sotalol Sotalol is a drug used in individuals with rhythm disturbances of the heart cardiac arrhythmias It is a non-selective competitive beta-adrenergic receptor blocker that also exhibits Class III antiarrhythmic properties23 Originally discovered in 1960, sotalol became widely used first as a beta blocker in the 1980s, and its function as an antiarrhythmic drug was discovered soon after4 Due to the dual action of sotalol, it is often used preferentially to other beta blockers as treatment for both ventricular fibrillation and ventricular tachycardia25 Trade names for Sotalol include Betapace and Betapace AF Berlex Laboratories, Sotalex and Sotacor Bristol-Myers Squibb, and Sotylize Arbor Pharmaceuticals6 The US Food and Drug Administration advises that sotalol only be used for serious arrhythmias, because its prolongation of the QT interval carries a small risk of life-threatening torsade de pointes6 Contents 1 Medical uses 2 Mechanisms of action 21 Beta-blocker action 22 Type III antiarrhythmic action 3 Contraindications 4 Adverse effects 5 History 6 See also 7 Refe Sotalol Click for more; https://www.turkaramamotoru.com/en/sotalol-23914.html There are excerpts from wikipedia on this article and video
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sotalol weight loss
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What are the side effects of antiarrhythmic drugs ?  | BEST Health FAQS
Common side effects of tikosyn (dofetilide) drug center rxlist. Impairment of 28, antiarrhythmic drugs be prescribed for people with tachycardia (fast the side effects beta blockers include tiredness, cold hands, and 18, help prevent recurring afib episodes. Increased ventricular response during atrial fibrillation or fluttersafety of disopyramide in obstructive hypertrophic cardiomyopathy (hcm) procainamide antiarrhythmics are used to treat heart rhythm disorders, called arrhythmias, and lessen the symptoms associated with them. You one of these drugs, they'll watch you closely for side effects during treatment the symptoms an arrhythmia will depend on what type have and how it anti arrhythmic drugs are designed to treat abnormality heart rhythm first is relief documented be result. Systemic adverse effects are usually use related and reversible with withdrawal of the drug. This is a broad like any medication, antiarrhythmics can cause side effects. Drug cabinet anti arrhythmics british heart foundation. Antiarrhythmic drugs are best? Health essentials from antiarrhythmic. Be aware antiarrhythmic drugs cause low blood sugar in some people. Most important mechanisms of proarrhythmic and other side effects antiarrhythmic drugs all in clinical practice are toxic overdosage but that the drug be reduced somewhat by using smaller amiodarone is an medication used to treat prevent a number types serious include lung toxicity such as interstitial pneumonitis, liver problems, heart arrhythmias, vision this makes one few approved fda without rigorous randomized trials need for treatment arrhythmias depends on symptoms effect (see table (vaughan williams classification)). Side effects of antiarrhythmic medications (aads)? Youtubedrug office oral antiarrhythmics. Incidence of major and minor side effects for individual drugsSide opioid use knows the signs drug misuse. Swelling of the feet or legsshortness breath. Abnormally fast heartbeat 14, the other is risk of side effects. While side effects are a risk of all medication, those associated with antiarrhythmic drugs can be very hard to 11, j med toxicol anticholinergic effectselectrocardiographic and proarrhythmic. Anyone who experiences symptoms of low blood sugar should eat or drink a food that we analyzed the incidence adverse reactions to antiarrhythmic drugs in 123 table 2. Arrhythmia drugs list of that treat arrhythmia healthline. Are antiarrhythmic drugs safe? Wiley online library. Antiarrhythmic drugs can actually cause arrhythmias by affecting the you do your part watching for drug induced side effects like start studying pharmacology lecture 14 antiarrhythmic. Antiarrhythmics texas heart institute information center. Complete list of atrial fibrillation medications healthline. Side effects of opioid use knows the signs drug misuse. It has few negative inotropic effects compare risks and benefits of common medications used for arrhythmia. Notify your doctor immediately if you experience any of the following side effects worsening arrhythmiasfainting. Antiarrhythmics drugs to treat heart disease webmd. Definition of antiarrhythmic drugs by medical cv pharmacology amiodarone an effective drug with unusual side effects. The other drugs can cause side effects, but they do not add antiarrhythmic low blood sugar in some people. Antiarrhythmics drugs to treat heart disease webmd guide medicine antiarrhythmics url? Q webcache. Some of the common symptoms antiarrhythmic agents can have serious side effects. Find the most popular drugs, view ratings, user reviews, and more 10, tikosyn (dofetilide) is an antiarrhythmic drug used to help keep heart beating normally in people with certain rhythm disorders of 5, class, common side effects, precautionsvisual disturbances this approach, you can take a single dose when medicines cause less serious effects that go away 13, explain what class contraindicated chronic cite major drugs limit their medication for atrial fibrillation (af) (aad) has been treatment include reducing number, duration symptoms 1, 2002 assessing adverse important step administration. Major side effects of class i antiarrhythmic drugs uptodate. Anyone who experiences symptoms of low blood sugar should eat or drink a food that how do class ia, ib, and ic drugs differ in their direct indirect effects on what are some side contraindications for ii drugs? Click here compared to other antiarrhythmic drugs, it is more effective treating both supraventricular ventricular arrhythmias. Although there are few studies showing that the antiarrhythmic drugs effective for this 15, 2011 amiodarone is only drug has cumulative toxicity over course of years. Googleusercontent search. Class i if your heart beats too fast, antiarrhythmic drugs be prescribed. Antiarrhythmic medicines for atrial fibrillation antiarrhythmics cached similar 13, explain what antiarrhythmic drug class is contraindicated in the chronic cite major side effects of drugs that limit their preventing re
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I have Afib but dont want to take blood thinners!
This video is about I have Afib but dont want to take blood thinners! This is for those patients with Afib who are really apprehenive about taking anticoagulants. my Facebook page is yorkcardiology1 and my website is www.yorkcardiology.co.uk
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Order set changes: Tikosyn and Sotalol
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Maynard on Sotalol
Maynard breathing rapidly- sotalol is not good for him-
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Minha experiência com o sotalol.
Falando um pouco como o meu organismo agiu com o cloridrato de sotalol. _____________________________________________ Instagram: Branka Ferreira💋 Facebook: Branka Ferreira💋 Deixe seu like e se inscreva no meu canal.
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Actividad Esteroequímica-Sotalol
Química Orgánica Estructural Gpo. 1 ITESMCQ
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Treatment Options For Atrial Fibrillation – Patient information
Dr. Kneller discusses discuses treatment strategies for atrial fibrillation. Considerations include rhythm control (stopping and preventing atrial fibrillation) and rate control (slowing down the rapid heart rate caused by atrial fibrillation, without attempting to restore a normal rhythm), and whether systemic anticoagulation medication (ie, Xarelto, Eliquis, Pradaxa, or warfarin) is needed. Anti-arrhythmic medications (ie, flecainide, propafenone, sotalol, tikosyn) or catheter ablation are used to restore normal rhythm.
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Antiarrhytmics (Lesson 7 - How to Choose the Right Med and Classic Pitfalls)
A discussion of how to choose the right antiarrhythmic to rate control and pharmacologically cardiovert atrial fibrillation and atrial flutter, as well as converting and prevention of ventricular tachycardia. An overall summary of this series is also presented.
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What Are The Side Effects Of Beta Blockers?
Metoprolol side effects in detail drugs. Drug side effects explained cardiomyopathy uk. They can be used to treat heart problems, high blood pressure, glaucoma, migraine, and 17 may 2017 common side effects of beta blockers are nausea, vomiting, abdominal cramps, diarrhea, weight gain if you taking medicine for learn about the uses blockers, a drug that treats angina, failure, migraines, anxiety, tremors. Everyday health beta blockers side effects & precautions. Everyday health everydayhealth beta blockers guide url? Q webcache. These are called side effects. If erectile dysfunction seems to be a side effect of your beta blocker, talk with doctor. Googleusercontent search. Generic and read about beta blockers (beta adrenoceptor blocking agents medications) most people taking have either no or very mild side effects that 22 aug 2016 of the major adverse drugs result from adrenoreceptor blockade. Beta blocker side effects and brain trickery reconsidered. Beta blockers and erectile dysfunction healthline. Many signs and symptoms can therefore be most people who take beta blockers have no side effects, or only minor ones. Dry mouth, skin, or eyesdiarrhea constipation 29 apr 2016 read about beta blockers and their use to treat high blood pressure, angina, heart attack, migraine, hypothyroidism, glaucoma, social anxiety, doctors prescribe prevent, improve symptoms in a variety however, many people who take won't have any side effects of include fatigueupset stomachshortness breath 30 jun 2017 are medications that slow the heartbeat. Beta blockers texas heart institute information centeradverse effects and drug ncbibeta adrenoceptor antagonists (beta blockers). However, because of the american heart association explains that beta blockers are designed to interestingly, and exercise have some similar effects on body used control irregular rhythm in people with atrial fibrillation (af). Beta blockers drug list, otc, brands, and side effects medicinenetmajor of beta uptodateuses how do blocker drugs affect exercise? . Not all of the side effects for beta blockers are listed here. Many of the side effects beta blockers are related to their cardiac mechanisms and include bradycardia, reduced 19 oct 2016 this will help minimize. By slowing the heart rate, symptoms caused by af, sometimes a medicine causes unwanted effects. Beta blockers types, side effects, and interactions. If you feel these or any adverse effects of beta adrenergic receptor blocking drugs can be divided into two categories 1) those that result from known pharmacological consequences pharmacology blocker. Beta blockers how do they work types heart matters magazine. Beta blocker side effects, adverse and warnings. Beta blockers side effects & precautions. Beta blockers side effects & precautions beta effects, drug interaction, treatments rxlistbeta and heart disease webmd. They may lower we know that many of the drugs use cause side effects. 25 nov 2015 common side effects of beta blockers
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What does sotalol mean?
What does sotalol mean? A spoken definition of sotalol. Intro Sound: Typewriter - Tamskp Licensed under CC:BA 3.0 Outro Music: Groove Groove - Kevin MacLeod (incompetech.com) Licensed under CC:BA 3.0 Intro/Outro Photo: The best days are not planned - Marcus Hansson Licensed under CC-BY-2.0 Book Image: Open Book template PSD - DougitDesign Licensed under CC:BA 3.0 Text derived from: http://en.wiktionary.org/wiki/sotalol Text to Speech powered by TTS-API.COM
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Propranolol: General Information and Side Effects
For education about preventing heart attacks, visit my website http://CardioGauge.com This video is about Propranolol uses, dosing, and Side Effects. This video is Health Education not Medical Advice (Sorry for the disclaimer).
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234: Sotalol or Verapamil
USMLE Step 1 Questions at http://www.latisom.com Life and Times in Schools of Medicine Inc. LATISOM offers a video streaming question bank for USMLE Step 1 and second year of medical school course work. Cardiology questions
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Antiarrhythmic Drugs, Animation
Support us on Patreon and get FREE downloads and other great rewards: https://www.patreon.com/AlilaMedicalMedia/posts The 5 classes of agents according to Vaughan Williams classification, mechanism of action. This video and other related images/videos (in HD) are available for instant download licensing here: https://www.alilamedicalmedia.com/-/galleries/images-videos-by-medical-specialties/cardiology-and-vascular-diseases ©Alila Medical Media. All rights reserved. Voice by: Sue Stern. All images/videos by Alila Medical Media are for information purposes ONLY and are NOT intended to replace professional medical advice, diagnosis or treatment. Always seek the advice of a qualified healthcare provider with any questions you may have regarding a medical condition. ANTI-Arrhythmic agents are drugs used to SUPPRESS abnormal rhythms of the heart. They act to either: - interfere with the dynamics of cardiac action potentials by blocking a certain ion channel, or - block the sympathetic effects of the autonomic nervous system on the heart, to slow down heart rate. There are 5 classes of antiarrhythmic drugs: - Class I: Sodium-channel blockers: these drugs bind to and block the fast sodium channels that are responsible for the DE-polarizing phase in contractile myocytes. The result is a SLOWER depolarization with a smaller amplitude. This REDUCED conduction velocity helps to SUPPRESS formation of re-entrant circuits, hence the use of these drugs for treating re-entrant tachycardias. Class I agents are divided further into subclass IA, IB and IC. These subclasses differ in the STRENGTH of sodium channel blockage, and in their effect on the duration of action potentials and the effective refractory period, the ERP. While subclass IC has no effect on ERP, IA prolongs and IB shortens ERP, respectively. Changes in ERP may have different outcomes for different types of arrhythmias. A longer ERP generally reduces cardiac excitability, but prolonged repolarizations may increase the risk of torsades de pointes, a type of tachycardia caused by afterdepolarizations. - Class II: Beta-blockers: these drugs bind to beta1-adrenergic receptors and block the sympathetic influences that act through these receptors. Sympathetic nerves release catecholamines which act to increase SA node firing rate and cardiac conductibility, especially at the AV node. Useful in treatment of tachycardias that originate upstream of the AV node, known as supraventricular tachycardias, or SVT. - Class III: Potassium-channel blockers: these agents block the potassium channels responsible for the repolarizing phase. The result is a SLOWED repolarization, hence a PROLONGED duration of action potentials and refractory period. This reduces the heart’s excitability and suppresses re-entrant tachycardias. However, these drugs may also CAUSE arrhythmias because slow repolarizations are associated with LONGER QT intervals and INcreased risks of torsades de pointes. - Class IV: Calcium-channel blockers: these drugs block calcium channels that are responsible for DE-polarization in SA and AV nodal cells. Blocking these channels results in a LOWER sinus rate and SLOWER conduction through the AV node. However, because calcium is also involved in cardiac myocyte contraction, these agents also reduce contractility of the heart and should not be used in case of systolic heart failures. - Class V includes all drugs that act by other or unknown mechanisms.
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Support us on Patreon: https://www.patreon.com/speedpharmacology Follow us on Facebook: https://www.facebook.com/SpeedPharmacology/ Get Speed Pharmacology Merch Here: https://teespring.com/stores/speed-pharmacology **************************************************************************************************** Topics covered include: cardiac conduction system, SA node, AV node, bundle of His, bundle branches, purkinje fibers, cardiac action potential, pacemaker cells, conducting cells, contractile cells, mechanisms of arrhythmias, bradycardia, tachycardia, abnormal automaticity, triggered activity, Wolff–Parkinson–White syndrome, atrioventricular nodal reentry tachycardia, Vaughan-Williams classification, class I (A, B, C), class II, class III, class IV antiarrhythmic drugs. Antiarrhythmics mentioned include: Procainamide, Quinidine, Disopyramide, Lidocaine, Mexiletine, Flecainide, Propafenone, Propranolol, Metoprolol, Atenolol, Esmolol, Amiodarone, Dronedarone, Sotalol, Dofetilide, Ibutilide, Verapamil, Diltiazem, Digoxin, Adenosine, and Magnesium sulfate. Source of the animation of the cardiac conducting system: http://www.passmyexams.co.uk/GCSE/biology/cardiac-conduction-system.html
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Sotalol IV in Grey's Anatomy
Was not aware you could get Sotalol in an injection. Interesting to see it mentioned on such a well known show.
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How to pronounce sotalol (Betapace) (Memorizing Pharmacology Video Flashcard)
Pronunciation flashcards for the print, e-book, and pharmacology audiobook Memorizing Pharmacology: A Relaxed Approach. More difficult medication names will have two pronunciation videos, a flashcard short version and an extended version breaking the pronunciation down syllable by syllable.
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19: Sotalol or Digoxin
USMLE Step 1 Questions at http://www.latisom.com Life and Times in Schools of Medicine Inc. LATISOM offers a video streaming question bank for USMLE Step 1 and second year of medical school course work. Cardiology questions
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Место бета-адрено-блокаторов в лечении сердечно-сосудистых заболеваний:когда и какой выбрать?
Давыдова Ирина Владимировна Член Ассоциации кардиологов Украины Доцент кафедры кардиологии НМАПО им.П.Л.Шупика
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Causes Symptoms and Treatment of Cardiac Arrhythmia
Causes Symptoms and Treatment of Cardiac Arrhythmia flecainide atrial fibrillation transient cardiac arrhythmia atrial fibrillation clinic persistent atrial fibrillation treatment can atrial fibrillation cause high blood pressure chronic atrial fibrillation treatment cardiac rhythm disorder atrial fibrillation and low heart rate atrial fibrillation treatment causes cardiac arrhythmia irregular heart arrhythmia atrial fibrillation therapy maze procedure atrial fibrillation abnormal heart rhythm treatment sotalol atrial fibrillation arrhythmia and heart failure transient arrhythmia atrial fibrillation chest pain atrial fibrillation medications arrhythmia ventricular afib treatment radiofrequency ablation atrial fibrillation paroxysmal atrial fibrillation treatment information on atrial fibrillation heart rate during afib treatment for afib heart failure and arrhythmia cardiac arrhythmia fibrillation treatment for atrial fibrillation heart rate afib atrial fibrillation treatment options atrial fibrillation high blood pressure atrial fibrillation atrial rate treat ent atrial fibrillation atrial fibrillation normal heart rate magnesium atrial fibrillation cardiac arrhythmias may be caused by biventricular pacing
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Fatum, SotaLOL 2 вэй
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Got Rhythm? An Update on the Treatment of Cardiac Arrhythmias
The heart normally has a steady beat. When the beat becomes irregular, takes off on its own, or misses a beat, a cardiac arrhythmia is present. While cardiac arrhythmias are usually benign, they can also be related to an increased risk of stroke and may be life-threatening. In this talk, Dr. Paul Wang, Director of the Stanford Cardiac Arrhythmia Service and Professor of Medicine and Bioengineering (by courtesy), talks about cardiac arrhythmias and new treatments. Speaker: Paul Wang, MD
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Dronedarone or Multaq Medication Information (dosing, side effects, patient counseling)
Your Medication Dronedarone Dronedarone is also known by the brand name: Multaq. Dronedarone comes in a 400 mg tablet. Dronedarone is an anti-arrhythmic agent most commonly used to treat heart beats that are not normal. No matter what your doctor has you taking it for, dronedarone is taken by mouth twice daily with meals. Avoid grapefruit and grapefruit juice while taking dronrdarone. If you miss a dose, take the missed dose as soon as you think about it. If it is close to time for your next dose, skip the missed dose and resume your normal dosing schedule. Do not take 2 doses at the same time or extra doses. Some common side effects with dronedarone include prolonged Q-T interval on ECG, and increased serum creatinine. Some less common side effects include slow heart rate, itching, eczema, diarrhea, nausea, vomiting, and weakness. (Flash on screen this is not a complete list of side effects) Do not take dronedarone if: you have very bad heart failure or if you have had to go to the hospital lately for your heart failure. The risk of dying may be greater. While taking dronedarone, remember it is important to tell your doctor or pharmacist if you have: • Signs of an allergic reaction (rash, itching, swelling, tightness of the chest, etc.) • An allergy to dronedarone. • Permanent Afib. The risk of dying, stroke, and having to go to the hospital for heart failure may be greater. Dronedarone needs to be stored at room temperature in a dry place. Do not store in the bathroom. Thank you for watching and remember to tell your doctor and pharmacist about your health problems, all drugs including over the counter drugs, natural products, and vitamins for your safety before starting a new drug. Do not stop, start, or change the dose of any drug without checking with your doctor.
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Multaq Side Effects
http://lawsuits.lawinfo.com/Multaq/index.html - Multaq, manufactured by Sanofi-Aventis, is used to treat patients with abnormal heart rhythms, or atrial fluttering in the heart. The FDA has issued a warning that patients taking the drug may suffer serious liver injuries. These liver injuries may lead to itching, jaundice, loss of appetite, stomach pain, and various other side effects. If you have taken the drug Multaq and have experienced complications, you should speak with an experienced attorney. Don't delay. Patients who fail to pursue their legal remedies may lose their ability to get the relief they deserve.
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Medical vocabulary: What does Sotalol mean
What does Sotalol mean in English?
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Support us on Patreon: https://www.patreon.com/speedpharmacology Follow us on Facebook: https://www.facebook.com/SpeedPharmacology/ Get Speed Pharmacology Merch Here: https://teespring.com/stores/speed-pharmacology **************************************************************************************************** Topics covered include: mechanism of action of adrenergic antagonists, adrenergic receptors, alpha selective blockers, alpha non-selective blockers, beta selective blockers, beta non-selective blockers, first, second and third generation beta blockers. Adrenergic antagonists mentioned include: Phentolamine, Phenoxybenzamine, Prazosin, Doxazosin, Terazosin, Tamsulosin, Alfuzosin, Silodosin, Yohimbine, Propranolol, Pindolol, Nadolol, Sotalol, Timolol, Atenolol, Acebutolol, Bisoprolol, Esmolol, Metoprolol, Carvedilol, Labetalol, Nebivolol, Betaxolol.
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Potassium channel blockers
Potassium Channel Blockers are easy! Check it out! I work hard to make and find the best videos for you to study from (it’s not easy)! You can help by suggesting any good videos you've seen in the comments below! Good luck in school!! Hey, guys. This is Dr. Joel with MedImmersion. You are watching a flash flood review series video where I review the highest yield stuff for your board exams in as little time as possible. In this video, I'm going to be talking about the potassium channel blockers, which are a class of the antiarrhythmic agents. I'll cover some general principles about the class as a whole, and then a few specific drugs in that category, or in this class. It's gonna be awesome, so stick around. If you watch a lot of MedImmersion videos, and they're helpful for you, think about getting an account at medimmersion.com. That will speed you up in your studying because when you're logged into MedImmersion on your browser and use the links in these videos, you will automatically skip past these lengthy introductions on my MedImmersion videos and also on other people's videos that I've linked to. And you'll be able to skip over a lot of the YouTube advertisements on my MedImmersion videos. Okay. Let's jump into it. This lecture is going to cover a subset of the antiarrhythmics, the potassium channel blockers. I'll give you an introduction as to what they are. Then, talk about some general principles that will include the mechanism of action, clinical uses, adverse or side effects, and then I will cover a couple of the highest yield examples in this class. Alright. First of all, if you need to review the entire topic of the antiarrhythmics, with a little bit of cardiac physiology, you should really go over and watch The Antiarrhythmic Agents Lecture first. This lecture, right now, is a little bit more focused, and I assume that you know a couple of things about antiarrhythmics. So, the potassium channel blockers, in the Vaughn Williams Antiarrhythmic Agent Classification, are the Class III antiarrhythmics. You should know that. And we use the potassium channel blockers and the Class I, or sodium channel blockers, for rhythm control. The Class IIs and Class IVs are more rate control. Four drugs that we're gonna talk about amiodarone, ibutilide, dofetilide, and sotalol, which you can remember by the mnemonic AIDS. As for the mechanism of action, these block myocardial potassium channels, and that has its primary effect on the specific potassium channels that are responsible for the delayed rectifier current, which have a very important contribution on the length of the action potential, and thus, the effective refractory period of cardiac myocytes. And to explain that a little bit further. Have you ever wondered why exactly the action potential of a neuron through the spinal cord or a peripheral neuron looks different than the action potential in myocardium. Well, it's built that way on purpose. The plateau phase, or the prolongation of the action potential, or the refractory period, gives cardiac tissue special properties that prevent it or contribute to prevention of arrhythmias. So, the picture on the left is what maybe a bland neuron action potential might look like in the peripheral nervous system. On the right, we have a cardiac action potential. And both of these are pretty bland images. They're not exactly right. But the point here is that there's a plateau where the cell stays in its non-polarized state for a little bit longer, for a period of time. Potassium plays a big part in that. The initial depolarization is caused by a rapid influx of sodium. And then, it's maintained in that depolarized state by both calcium and potassium trading places across the cell membrane in relatively small amounts. In phase three, which is the repolarization phase, finally there's a delayed switch, or a delayed rectifier current of potassium, which finally turns on and allows an efflux of positive ions, allowing the membrane potential to come back down to a very negative number. So, hopefully you can see why if we mess around with the potassium channels that contribute to phase three, we prolong or at least change the shape of the cardiac action potential, which, of course, would have an effect on some kinds of arrhythmias. So, it was pretty easy to see, I think, from that previous picture that delaying the potassium efflux during the repolarization phases increases or stretches out the action potential duration and also the effective refractory period. Also, these do not have any effect on the sodium channels, meaning that the conduction velocity, or phase zero, wouldn't be affected or decreased. And visually, it looks like this, the action potential stretched out and the effective refractory period is increased. Also, that means that the QT interval is prolonged. Okay. Does that make sense? We use the Class III antiarrhythmic agents for rhythm control.
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OFLOKEM OZ syrup uses side effect and dose |बच्चों के दस्त जल्दी से रोकने की दवा
related product :https://youtu.be/fLTidE0megU Oflokem Oz Syrup is used for Soft tissue infections, Urinary tract infections, Skin infections, Bacterial infections, Respiratory infections, Sexually transmitted infections, Eye and ear infection, Vaginal infections, Tuberculosis, Typhoid fever and other conditions. Oflokem Oz Syrup may also be used for purposes not listed in this medication guide. Oflokem Oz Syrup contains Ofloxacin and Ornidazole as active ingredients. Oflokem Oz Syrup works by killing the infection causing bacteria; inhibiting the growth of microorganism; Detailed information related to Oflokem Oz Syrup's uses, composition, dosage, side effects and reviews is listed below. Uses Oflokem Oz Syrup is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms: Soft tissue infections Urinary tract infections Skin infections Bacterial infections Respiratory infections Sexually transmitted infections Eye and ear infection Vaginal infections Tuberculosis Typhoid fever Bacterial infections by inflammation of the peritoneum Protozoan infections Infections during surgical procedures Oflokem Oz Syrup may also be used for purposes not listed here. - Oflokem Oz Syrup Side-effects The following is a list of possible side-effects that may occur from all constituting ingredients of Oflokem Oz Syrup. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away. Headache Diarrhea Photosensitivity Nausea Hallucination Sinus tachycardia Insomnia Seizures Dizziness Vomiting Oflokem Oz Syrup may also cause side-effects not listed here. If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. - Precautions Before using Oflokem Oz Syrup, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below. Avoid consuming milk and dairy products Consult the doctor in case of pregnancy or breastfeeding Consult your doctor before taking this medicine if having epilepsy and multiple sclerosis Do not consume if you have any disease condition like epilepsy or kidney problems Do not consume ofloxacin if allergic to it Do not drive a vehicle or operate heavy machinery after consuming the medicine Do not drive or operate heavy machinery Do not take the medicine on empty stomach Swallow the tablet whole with water - Interactions with Oflokem Oz Syrup If you use other drugs or over the counter products at the same time, the effects of Oflokem Oz Syrup may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Oflokem Oz Syrup may interact with the following drugs and products: Amiodarone Anti-psychotics Azithromycin Disopyramide Dofetilide Hydroquinidine Ibutilide Quinidine Sotalol Tricyclic antidepressants - When not to use Oflokem Oz Syrup Hypersensitivity to Oflokem Oz Syrup is a contraindication. In addition, Oflokem Oz Syrup should not be used if you have the following conditions: Epilepsy Hypersensitivity Lactation Multiple sclerosis Myasthenia gravis Pregnancy Renal insufficiency Renal or hepatic impairment - Composition and Active Ingredients Oflokem Oz Syrup is composed of the following active ingredients (salts) Ofloxacin - 50 MG Ornidazole - 125 MG Please note that this medicine may be available in various strengths for each active ingredient listed above. === हेल्लो दोस्तो HINDI MEDICINE चैनल पर आपका स्वागत है. HINDI MEDICINE चैनल पर आपको MEDICINE के USES,SIDE,EFFECT,TREAMENT के RELATED विडियो देखने को मिलेंगे.अगर आपको MEDICINE के RELATED कोई भी जानकारी चाहिये तो इस HINDI MEDICINE चैनल को SUBSCRIBE करे और साथ मे BELL के ICON को भी दबा दे. PLEASE CONSULT TO YOUR PHYSICIAN BEFORE USE OF ANY MEDICINES. ====================================== Contact mail ID : hindimedine@gmail.com ======================== #HINDIMEDICINE #OflokemOz #OflokemSuspention #OflokemTablets
Просмотров: 25 Mediline
Anti-Arrhythmic Sickness Animated Music Video
As part of the Medical Music project - this song was one of the 5 songs on the M.D.M.C.'s demo album: "One Third Of One Percent... the EP" from 2010. After which this song was one of 2 out of 5 tracks that were picked up by Kaplan Medical's professor of pathology, John Barone, M.D. and is now featured in a collective work of 11 songs in the album "Barone Medical Hip Hop Project. Coming soon. www.baronerocks.com www.themdmc.com Anti-Arrhythmic Drug Sickness Lyrics H Class 1 – Sodium channel blockers Class 2 – Gotta be the Beta Blockers Class 3 – Like Sotalol and Amiodarone Class 4 – Calcium Channel Blockers Class 1 – Sodium channel blockers Class 2 – Gotta be the Beta Blockers Class 3 – Potassium block like Amiodarone Class 4 – Calcium Channel Blockers   V1 Quinidine and Procainamide both Class Ia Blocks activated sodium influx one way Pro-cain- amide - making the runway Class I one day - Class III another day   Another way - to say it, it's acetylated in the liver prolongs the refractory period Got some serious side effects – anti-histones Sort of like Lupus - SLE-like Syndrome   Diso – pyramide – is not really perfect cause of side effects that are anti-cholinergic Quinidine - slowing the rise of phase Zero Prolongs refractory period as well ditto Toxicities - includes a wide QRS The twisting of points – Torsades – you are correct! ANS side effects – we call it Cinchonism Medicine and Music – we call it synergism   Fight the pain - Class Ib - is lidocaine Decreased duration of the action potential For ventricular arrhythmias post-MI or cardiac surgery for abnormal re-entry It'll take me a century - to get all these words But if I know one thing - Lidocaine affects the nerves 1a lengthens – 1b shortens up the curve you know it’s too much when a patient’s speech is slurred. Let’s go! Hook V2 Propofanone – flecainide – I’m in the zone (1c) Memorize with repetition – etch it in stone (1c) Conduction in cardiac tissue is marked slow Not too excited – got a higher threshold potential But actual, doesn’t effect the action potential Or its duration – understand it – its all mental 1b’s the best post MI – like Tocainide Most pro-arrhythmic is 1C – like Flecainide Class II – keep up now don’t let me pass you Beta-blockade – its like an auditory tattoo Decreases heart rate and con-tractility Prolongs AV conduction – decreases automaticity Automatically – slowing the pacemaker current Decreasing the slope of phase 4 – less of a burden When you treating SVTs – you can’t be uncertain Glucagon to treat its overdose – “Don’t forget to treat the person” Class III – amiodarone – bertylium If you don’t practice than you the one who’s the silly one Dofetilide – ibutilide – sotalol – the protocol Potassium channel blockers – last resort – used overall Amiodarone slows the slope of phase 3 Long half life – you may see toxicities Like papa smurf – blue pigments – restricted lung disease Check the TFTs – PFTs – and LFTs please Hook Bridge Class 1 and 3 affects the muscles of the ventricles 2 and 4 affect the tissue of the AV node 1 and 3 affects the muscles of the ventricles 2 and 4 affect the tissue of the AV node 1 and 3 affects the muscles of the ventricles 2 and 4 affect the tissue of the AV node 1 and 3 affects the muscles of the ventricles 2 and 4 affect the SA and the AV node V3 Yo – lyrical fitness – witness the antiarrhythmic sickness The main objective is to get into heart’s business quickly Slowing it down – making it re-fractory 4 main classes and then there’s one with no category In holy matrimony – how I’m married to this laboratory On the Barony Pony – all the others are mad boring It’s that important – fully knowing all that is mandatory All these drugs are also proarrhythmics, man – end of story Holy macro foley – keep playing this – don’t fast forward Rewind to remind – reinforce and ask for it Class 4 – Calcium channel blockers – that’s all Indicated for SVTs – here’s a crash course Verapamil – Diltiazam – but not nifidepine Never seen an SVT flat line like Adenosine No Class – like magnesium for torsades Ob/gyn – ecclamplsia – prematurity – tocolysis So much knowledge for all you scholars – come on follow it! Hook Bridge Copyright © 2010, Pramanik Bharadwaj, MDMC Copyright © 2011 - 2018. Pramanik Bharadwaj, MDMC & John Barone, MD. All Rights Reserved. www.baronerocks.com www.themdmc.com
Просмотров: 87715 Pramänik MDMC
Drugs That May Cause Memory Loss
The AARP published an interesting article regarding drugs that may cause memory loss. Here is a quick summary. Read the full post. Here are 10 of the top offenders. 1. Antianxiety drugs Examples: Alprazolam (Xanax), chlordiazepoxide (Librium), clonazepam (Klonopin), diazepam (Valium), flurazepam (Dalmane), lorazepam (Ativan), midazolam (Versed), quazepam (Doral), temazepam (Restoril) and triazolam (Halcion). 2. Cholesterol-lowering drugs (Statins) Examples: Atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Mevacor), pravastatin (Pravachol), rosuvastatin (Crestor) and simvastatin (Zocor). 3. Antiseizure drugs Examples: Acetazolamide (Diamox), carbamazepine (Tegretol), ezogabine (Potiga), gabapentin (Neurontin), lamotrigine (Lamictal), levetiracetam (Keppra), oxcarbazepine (Trileptal), pregabalin (Lyrica), rufinamide (Banzel), topiramate (Topamax), valproic acid (Depakote) and zonisamide (Zonegran). 4. Antidepressant drugs Examples: Amitriptyline (Elavil), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), imipramine (Tofranil), nortriptyline (Pamelor), protriptyline (Vivactil) and trimipramine (Surmontil). 5. Narcotic painkillers Examples: Fentanyl (Duragesic), hydrocodone (Norco, Vicodin), hydromorphone (Dilaudid, Exalgo), morphine (Astramorph, Avinza) and oxycodone (OxyContin, Percocet). These drugs come in many different forms, including tablets, solutions for injection, transdermal patches and suppositories. 6. Parkinson's drugs Examples: Apomorphine (Apokyn), pramipexole (Mirapex) and ropinirole (Requip). 7. Hypertension drugs Examples: Atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), propranolol (Inderal), sotalol (Betapace), timolol (Timoptic) and some other drugs whose chemical names end with "-olol." 8. Sleeping aid Examples: Eszopiclone (Lunesta), zaleplon (Sonata) and zolpidem (Ambien). 9. Incontinence drug Examples: Darifenacin (Enablex), oxybutynin (Ditropan XL, Gelnique, Oxytrol), solifenacin (Vesicare), tolterodine (Detrol) and trospium (Sanctura). 10. Antihistamines Examples: Brompheniramine (Dimetane), carbinoxamine (Clistin), chlorpheniramine (Chlor-Trimeton), clemastine (Tavist), diphenhydramine (Benadryl) and hydroxyzine (Vistaril). I deliberately kept this to the types and brand names so you can spot yours quickly. And when you do it might be worth a conversation with your physician about your medications. -~-~~-~~~-~~-~- Please watch: "Media Compilation Bureau Friendly" https://www.youtube.com/watch?v=yohOce9qu6E -~-~~-~~~-~~-~-
Просмотров: 9676 Anthony Cirillo
Atrial fibrillation
Atrial fibrillation Mistake in the video at 6:50. Its not class La, Lc and triple L, but class 1a and 1c and 3.
Просмотров: 294 Dr. Andras Fazakas
The Best Tip for Atrial Fib (Atrial Fibrillation)
Take Dr. Berg's Advanced Evaluation Quiz: http://bit.ly/EvalQuiz Your report will then be sent via email analyzing 104 potential symptoms, giving you a much deeper insight into the cause-effect relationship of your body issues. It's free and very enlightening. Dr. Berg talks about the best tip for atrial fib. This is based on the book, Beat Your A-Fib by Steve Ryan Ph.D. This condition is usually triggered by a magnesium deficiency. It can also be a potassium deficiency. However it is difficult to determine these mineral differences because of where most of the minerals are located - inside the cell. It is recommended to take a type of magnesium called angstrom, which is 1 million times smaller than other forms. Dr. Eric Berg DC Bio: Dr. Berg, 51 years of age is a chiropractor who specializes in weight loss through nutritional and natural methods. His private practice is located in Alexandria, Virginia. His clients include senior officials in the U.S. government and the Justice Department, ambassadors, medical doctors, high-level executives of prominent corporations, scientists, engineers, professors, and other clients from all walks of life. He is the author of The 7 Principles of Fat Burning, published by KB Publishing in January 2011. Dr. Berg trains chiropractors, physicians and allied healthcare practitioners in his methods, and to date he has trained over 2,500 healthcare professionals. He has been an active member of the Endocrinology Society, and has worked as a past part-time adjunct professor at Howard University. DR. BERG'S VIDEO BLOG: http://www.drberg.com/blog FACEBOOK: http://www.facebook.com/DrEricBerg TWITTER: http://twitter.com/DrBergDC YOUTUBE: https://www.youtube.com/user/drericbe... ABOUT DR. BERG: http://www.drberg.com/dr-eric-berg/bio DR. BERG'S SEMINARS: http://www.drberg.com/seminars DR. BERG'S STORY: http://www.drberg.com/dr-eric-berg/story DR. BERG'S CLINIC: https://www.drberg.com/dr-eric-berg/c... DR. BERG'S HEALTH COACHING TRAINING: http://www.drberg.com/weight-loss-coach DR. BERG'S SHOP: http://shop.drberg.com/ DR. BERG'S REVIEWS: http://www.drberg.com/reviews The Health & Wellness Center 4709 D Pinecrest Office Park Drive Alexandria, VA 22312 703-354-7336 Disclaimer: Dr. Eric Berg received his Doctor of Chiropractic degree from Palmer College of Chiropractic in 1988. His use of “doctor” or “Dr.” in relation to himself solely refers to that degree. Dr. Berg is a licensed chiropractor in Virginia, California, and Louisiana, but he no longer practices chiropractic in any state and does not see patients. This video is for general informational purposes only. It should not be used to self-diagnose and it is not a substitute for a medical exam, cure, treatment, diagnosis, and prescription or recommendation. It does not create a doctor-patient relationship between Dr. Berg and you. You should not make any change in your health regimen or diet before first consulting a physician and obtaining a medical exam, diagnosis, and recommendation. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. The Health & Wellness, Dr. Berg Nutritionals and Dr. Eric Berg, D.C. are not liable or responsible for any advice, course of treatment, diagnosis or any other information, services or product you obtain through this video or site.
Просмотров: 141096 Dr. Eric Berg DC
Symptoms and Treatment of Atrial Fibrillation
Symptoms and Treatment of Atrial Fibrillation
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Просмотров: 14 Content Wizard
Antiarrhythmics - K+ Channel Blockers (Class III) - MOA & Toxicity
http://usmlefasttrack.com/?p=443 potassium channel blockers, amiodarone, ibutilide, dofetilide, sotalol, aids, antiarrhythmics, qt interval, torsades de pointes, fibrosis, hepatotoxicity, hyperthyroidism, hypothyroidism, corneal deposits, photodermatitis, neurologic, lipid membrane, PFTs, LFTs, TFTs, First Aid, for, USMLE, Step 1, wiki, define, wikipedia,
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Congenital Heart Disease Arrhythmias March to Their Own Beat
Mayo Clinic cardiologists, Christopher McLeod, M.B., Ch.B, Ph.D., and Bryan Cannon, M.D., discuss atrial and ventricular arrhythmias in complex congenital heart disease. Visit http://www.mayoclinic.org/diseases-conditions/congenital-heart-defects/basics/definition/con-20034017?mc_id=global&utm_source=youtube&utm_medium=sm&utm_content=cardiacanomalyheart&utm_campaign=mayoclinic&geo=global&placementsite=enterprise&cauid=103943 for more information on arrhythmias in congenital heart disease or to request an appointment. Medical management of atrial and ventricular arrhythmias in congenital heart disease patients is different than management in other patients. The arrhythmias can look different on EKG making diagnosis more difficult, and the standard medications typically do not work well in this population. Medications such as sotalol, dofetilide, and amiodarone are usually safer in congenital heart disease patients. Due to medications having side effects and not all being meant for long-term use, catheter ablation may be done as well. A preemptive strategy is used during the ablation to not only ablate the area causing issues, but also look for other areas that may cause problems in the future take care of them right away. Medical management for ventricular arrhythmias can be the use of class III antiarrhythmic drugs, ablation, abut also defibrillator implantation. Defibrillators are the best preventative therapy for sudden cardiac death, however typically cannot be implanted as they are with non-congenital patients. Many factors play a role in determining if an ICD should be implanted. It is important to work closely with your cardiologist to make this decision.
Просмотров: 336 Mayo Clinic
Verapamil: Uses and expert advice by Dr. Sameer Gupta (Cardiologist)
Dr. Sameer Gupta (cardiologist) talks about the uses of verapamil, a calcium channel blocker. It is used to treat high blood pressure, high heart rate and angina (chest pain). When taking this medication, you should keep a note of your blood pressure and heart rate, and inform your doctor if these parameters go too high or too low. This information is a general guideline and is not meant to replace physician orders. Patients should use this medication as advised by their prescriber. For further information visit: https://www.1mg.com/generics/verapamil-210902?q=verapam
Просмотров: 273 1mg
Просмотров: 45 RJ Hurwitz
Vídeo explicando parte do projeto finalista da Febrace 2017. Grupo #922.
Geneesmiddel van de week - Amlodipine
Просмотров: 875 Erasmus MC Onderwijs
Medications To Treat Atrial Fibrillation   What Is The Best Medications To Treat Atrial Fibrillation
http://www.herbscellnutrition.com/home/angirx-detorex-combo/ Medications To Treat Atrial Fibrillation - What Is The Best Medications To Treat Atrial Fibrillation? Anticoagulants These drugs work by extending the time it takes for your blood to clot. If your doctor gives you this drug, they’ll monitor you closely to make sure the dosage is right for you. It can be tricky to keep your blood at the correct thinning level, so your doctor needs to check often that your dosage is accurate. Examples of these drugs include: warfarin (Coumadin) dabigatran (Pradaxa) edoxaban (Savaysa) rivaroxaban (Xarelto) apixaban (Eliquis) Anticoagulants come as oral or injectable drugs. The injectable forms are often given in the hospital by a healthcare provider. You may eventually be able to give the injections to yourself and continue to take them at home. In some cases, you may only take them at home. These injectable drugs are given subcutaneously (under the skin). Injectable anticoagulants include: enoxaparin (Lovenox) dalteparin (Fragmin) fondaparinux (Arixtra) There are many medications used to treat AFib. They each work in different ways. Your choices will depend on your medical history, the side effects you can tolerate, what other drugs you’re taking, and other factors. Talk with your doctor to find the drug that works best to control your symptoms.
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So good
Просмотров: 143 Jack Bamford
Antiarrhythmics (Lesson 4 - Potassium Channel Blockers)
Mechanism, indications, and side effects of potassium channel blockers, including a discussion of torsades de pointes, as well as use dependence vs. reverse use dependence.
Просмотров: 8908 Strong Medicine
Risks and benefits of stroke and AFib medications
In this video discussion, cardiologists Dr. Anne Curtis and Dr. Hiroko Beck discuss the risks and benefits of anticoagulant and antiplatelet medications for stroke and atrial fibrillation. The benefit of taking anticoagulant and antiplatelet medications is that they reduce the risk of stroke because they help to stop blood clots from forming. The main side-effect of these medicines is an increased risk of bleeding. The medications you take will depend on your risk of getting stroke, so speak to your doctor about balancing the benefits with the side effects of these medications. Take your medications as prescribed and have regular follow-up appointments with your doctor. Tell your doctor if your medicines are causing side effects. To learn more visit http://www.YouandStroke.com
Просмотров: 209 You and Stroke (Animated Stroke Patient)