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Mesalamine Dose May Lower Marker of Bowel Inflammation - IBD in the News
Edward Loftus Jr., M. D., a gastroenterologist at Mayo Clinic, discusses a recent article published in Clinical Gastroenterology and Hepatology looking at the ability of a drug driving down calprotectin, a marker of bowel inflammation, in ulcerative colitis patients.
Просмотров: 5798 Mayo Clinic
Should I take prednisone/asacol/mesalamine or change my lifestyle?
What are you going to choose? As Always LIKE | SHARE | SUBSCRIBE & Stay Highcarb Healthy! Colitis & Crohns Recovery Program: http://www.highcarbhealth.com/colitis-crohns-program/ Testimonials: http://www.highcarbhealth.com/testimonials/ Self Healing Colitis & Crohns: http://www.highcarbhealth.com/ebooks/ Strava Cycling: https://www.strava.com/athletes/4289527 DOCUMENTARIES: https://www.forksoverknives.com/ http://www.whatthehealthfilm.com/ http://www.cowspiracy.com/ Follow me on social so you get an idea of what I do and what I eat: Snapchat: denzo11 Instagram Stories: @highcarbvegans ☆ http://www.highcarbhealth.com/ ☆ https://www.facebook.com/highcarbvegan ☆ https://twitter.com/highcarbvegans ☆ http://instagram.com/highcarbvegans DISCLAIMER: FAIR USE NOTICE this video may contain copyrighted material. Such material is made available for educational purposes only. This constitutes a 'fair use' of any such copyrighted material as provided for in Title 17 U.S.C. section 106A-117 of the US Copyright Law.
Просмотров: 1553 High Carb Health
MY LIFE WITH UC | Commonly Used IBD Medications
Making the decision to start drug treatment for UC can be really complicated. It is really important for you to be part of making decisions like these. There are a lot of things you need to consider when choosing a treatment, like, possible side effects, risks, cost and how quickly you should expect to see improvement. If you don’t know what UC is, please watch my “What is UC" video first. It will make it easier to follow along with this video. What is UC? https://www.youtube.com/watch?v=RgTIdDuxuHs&t=1s Here is a run down on all the drugs available today for treating UC, and everything you need to consider before taking them! 1:40 Benefits 2:10 5-ASA's 3:12 Sulfasalazine (salazopryrin, azulfidine) 4:15 Delayed-Release Mesalamine (asacol, pentasa, salofalk, mezavant, lalda) 5:30 Balsalsazide (colazide) 5:56 Olsalazine (dipentum) 6:25 Steroids 7:37 Prednisone 9:15 Methylprednisolone (solu-medrol) 9:45 Hydrocortisone, prednisolone, Betamethasone (betnesol) 10:02 Budesonide (entocort) 10:23 Immunosupressants 10:50 Azathioprine (imuran) & 6-Mercaptopurine (purinethol) 11:50 Methotrexate 13:04 cyclosporine 13:19 Biologics & Biosimilars 14;51 Infliximab (remicade) 16:14 Adalimumab (Humira) 16:39 Certolizumab pegol (cimzia) 17:06 Golimumab (simponi) 17:15 Vedolizumab (entyvio) 17:53 BIOSIMILAR Infliximab-dyyb (inflectra) 19:03 Step-up Therapy 19:34 top down therapy 19:53 FMT (Fecal Microbiota Transplant) 20:46 Concluding thoughts! Big thank you to the Canadian Digestive Health Foundation :) cdhf.ca for all the top notch info!
Просмотров: 7774 Effie Siamalekas
I have ulcerative colitis | Hannah Witton
Alternative title: My Poo Disease. I was diagnosed with ulcerative colitis when I was 7 years old and here's my story. //Buy my book*: http://bit.ly/2kBvjja //Subscribe for weekly videos: https://goo.gl/XXaoae It only just occurred to me after uploading that I completely missed out one of my main symptoms - blood and mucus in the diarrhoea. So there's that. Thanks for watching! Hope you enjoyed the video! Support me on Patreon: http://www.patreon.com/hannahwitton Shop: http://hannahwitton.firebrandstores.com/ Twitter: https://twitter.com/hannahwitton Blog: http://hannahwitton.com/ Instagram: http://instagram.com/hannahwitton Snapchat: hannahwitton Tumblr: http://hannahwitton.tumblr.com/ Facebook: http://www.facebook.com/hannahwittonofficial Google Plus: http://google.com/+HannahWittonofficial EQUIPMENT* Main camera - Canon 80d: http://amzn.to/2kjK7Xj Lens - Sigma 18-35mm f1.8: http://amzn.to/2jNEUDW Microphone - H4n Zoom: http://amzn.to/2kjGRLK Vlog camera - Sony RX100 MIV: http://amzn.to/2k9lREZ *Affiliate links End music: Thursday and Snow (Reprise) by Blank & Kytt
Просмотров: 292655 Hannah Witton
I have an autoimmune disease: My Ulcerative Colitis Story
For most of my life I've had Ulcerative Colitis. Here is my story and how I manage my Ulcerative Colitis naturally & mindfully (even on meds) 🌺 Ulcerative Colitis Playlist: https://www.youtube.com/playlist?list=PLP7Ou7uUiYzA0sWpcFxV4A85LuQJU7s8Q More posts about UC: http://sarahbethyoga.tumblr.com/tagged/ulcerativecolitis Ulcerative Colitis, IBD or IBS. My Ulcerative Colitis Playlist: https://www.youtube.com/playlist?list=PLP7Ou7uUiYzA0sWpcFxV4A85LuQJU7s8Q ▶︎ Yoga for Bloating, Digestion, Ulcerative Colitis: https://youtu.be/IvAx7q2LKqk ▶︎ Yoga for Bloating: https://youtu.be/VuKkTta3R6c 🙊 Poo Pouri: http://amzn.to/21ECh7m 🌺 Ulcerative Colitis Playlist: https://www.youtube.com/playlist?list=PLP7Ou7uUiYzA0sWpcFxV4A85LuQJU7s8Q 😍 SUBSCRIBE for FREE yoga: http://bit.ly/sarahbethyoga Welcome to your modern day yoga channel by Sarah Beth Yoga where you can find clear & fuss free yoga videos ranging from short yoga routines to 30 minute yoga practices for all levels to help you get stronger, happier & healthier. Click for MORE free yoga each week: http://bit.ly/sarahbethyoga 🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸 💙 DOWNLOAD yoga videos in the SarahBethYoga APP with over 300+ ad-free yoga videos, and content *NOT on YouTube* like: •45-60 min Classes •Daily Yoga Calendars & Challenges •Programs including: Prenatal Yoga Program & TONE Yoga Program •Member-only Videos Membership logs in on ALL your devices including the EXCLUSIVE APP! Learn more & sign up here: http://www.SarahBethYoga.com 🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸 SOCIAL: 💙 Facebook: http://bit.ly/sbyonfb 💜 Instagram: http://bit.ly/sbyonig ❤️ Email updates & discounts: http://bit.ly/sbyNewsletter 🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸🔸 Disclaimer: Some links may be affiliate links which help support Sarah Beth to create content, however Sarah Beth only promotes products she truly likes and all opinions are her own. Sarah Beth from Sarah Beth Yoga LLC strongly recommends that you consult with your physician before beginning any exercise program. You should be in good physical condition and be able to participate in the exercise. You should understand that when participating in any exercise or exercise program, there is the possibility of physical injury. If you engage in this exercise or exercise program, you agree that you do so at your own risk, are voluntarily participating in these activities, assume all risk of injury to yourself, and agree to release and discharge
Просмотров: 56691 SarahBethYoga
5 FAQs About Crohn's Disease
5 FAQs About Crohn's Disease 1. Q: What is Crohn’s disease? A: Crohn’s disease is an inflammatory disease of the gastrointestinal (GI) tract. It can affect any area of the GI tract, from mouth to anus. Unfortunately, we don’t know yet what exactly causes Crohn’s disease, but we tend to think the cause is multifactorial. We know there is a genetic component for some populations, and there also seems to be an environmental role as well. There also may be an infectious etiology, but at this time, research is inconclusive. Crohn’s disease causes inflammation because the body is responding to some intrusion, but we’re not quite sure what that is at this time. The body mounts a very heavy inflammatory response and that response can have a big impact on the body. Common symptoms include diarrhea, fatigue, abdominal pain, bloody stool, and weight loss. Some people with Crohn’s have unexplained fevers or develop rashes. Crohn’s symptoms can make life very difficult when they are not well controlled with the right therapy. If untreated, Crohn’s can cause complications that severely impact the digestive tract and other areas of the body. . Q: How is Crohn’s typically treated? A: There are several different types of medicines that I’ll use to treat Crohn’s. I’ll decide which medication to use first based on how severe the patient’s condition is. One class of medication, mesalamine products, are basically anti-inflammatory medicines for the GI tract. I also may prescribe antibiotics, corticosteroids, immunomodulator therapy, and biological therapy. 3. Q: How do you decide which medication is best for each patient? A: The treatment I choose depends on how severe the Crohn’s is. If someone comes in with mild to moderate Crohn’s symptoms, I’ll probably start them on mesalamine products to get inflammation down, and we’ll see if that keeps the Crohn’s under control. The goal is to get the patients into remission and then onto maintenance therapy so they stay in remission. Sometimes, early on, I’ll prescribe steroids to bring their symptoms down and bring them into remission, and then I’ll use mesalamine products to maintain it. For patients with moderate to severe Crohn’s that doesn’t respond to other types of therapy, I’ll try immunomodulators or biological therapy. These can also work in patients who require multiple courses of steroids a year to get flares down, because it is not safe to be on long-term steroid use when other alternatives are available. Biologics target and block specific molecules that produce inflammation in the GI tract. They are very effective in keeping Crohn’s symptoms down in patients that need a higher level of treatment, although there are side effects to keep in mind, like a higher likelihood of developing infections. In very severe cases of Crohn’s, we may turn to surgery if the patient has developed complications, but in general we try to avoid surgery because patients will still usually have a recurrence of Crohn’s after their operation. 4. Q: Can you control Crohn’s symptoms with diet? A: There are two ways that diet is important for people with Crohn’s. First, Crohn’s can cause you to be deficient in the nutrients your body needs. Often in Crohn’s patients, the small intestine is inflamed, which makes it harder to digest vitamins, fats, and proteins. And people with Crohn’s might not have much of an appetite, which can make this worse. Your doctor may recommend that you take different vitamins and supplements to replenish necessary nutrients. Second, Crohn’s symptoms can be impacted by what foods you eat. Nothing about a special Crohn’s diet has been scientifically proven, but my patients find there are specific foods that can make symptoms better and worse. While it’s different for every patient, I usually advise that they avoid dairy products, fatty foods, and spicy foods. During a flare up, it’s best to eat low-fiber foods so the digestive system doesn’t have to work as hard. 5. Q: What do you wish your patients knew about Crohn’s disease? A: When I first see patients, I make sure to tell them that in most people, Crohn’s is a treatable disease and once you get it under control, it should stay that way. Thankfully, there are a lot of treatment options available. Working together with the patient, we tailor the best regimen for each individual to maximize the outcome and quality of life. Help us to be better SUBSCRIBE for more videos here: https://www.youtube.com/channel/UCAf3_EHAdrHMSxk6-7bHG9w?sub_confirmation=1 More from Tamam Health: -8 Symptoms of Rheumatoid Arthritis https://youtu.be/VnnvYaEuZVA -10 Early Signs of Lupus https://youtu.be/_uHju14c3NY -5 Common Symptoms Of Perimenopause https://youtu.be/R7jOfYE5TCA 5 FAQs About Crohn's Disease By TAMAM HEALTH
Просмотров: 26 Tamam Health
Curcumin vs Ulcerative Colitis
This randomized double-blind placebo controlled trial of 50 patients with active mild to moderate ulcerative colitis were selected after failing to respond to the maximum dose of mesalamine oral and topical therapy. Participants were selected from three different sites around the world in Cyprus, Hong Kong, and Israel. Patients were either given 3g/day of curcumin or placebo. After one month, 14 patients out of the 26 in the curcumin group (53.8%) achieved clinical remission at 4 weeks, compared with none in the placebo group (p=0.01). Clinical remission was defined as Simple Clinical Colitis Activity Index (SCCAI) score equal to or less than 2. All patients that were recruited for the study began with an SCCAI score equal to or greater than five and less than 12 and had an initially confirmed endoscopic and histologic diagnosis of ulcerative colitis. After the four weeks, endoscopic remission was also observed in 8 of the 22 patients in the curcumin group (36%), as not all patients agreed to an endoscopic examination as part of the study, as compared to none of the 16 patients in placebo group that agreed to an endoscopic examination (p=0.043). Unfortunately, it appears that consuming 3g of curcumin per day is not easily achieved using dietary levels of turmeric. It is estimated that the curcumin quantity within turmeric powder is about 3.14% ("Curcumin content of turmeric and curry powders" Nutrition Cancer 2006;55(2):126-31 - https://www.ncbi.nlm.nih.gov/pubmed/17044766). That works out to about 12-13 Tbsp of turmeric a day. The report states "In conclusion, the findings of this trial suggest that curcumin as add-on therapy with optimized mesalamine is superior to optimized mesalamine alone in inducing clinical remission in patients with active mild-to-moderate ulcerative colitis." Learn more by checking out p351 of Dr. Greger's book How Not to Die, or watch a related NutritionFacts.org video on Striking with the Root: Turmeric Curcumin and Ulcerative Colitis https://www.youtube.com/watch?v=teJ9QHCdN2Q This 2015 study was published in Clinical Gastroenterology and Hepatology vol 15, no. 8, p1444-49 "Curcumin in combination with mesalamine induces remission in patients with mild-to-moderate ulcerative colitis in a randomized controlled trial " by A Lang, N Saomon, JCY Wu et al. A free is available online at http://www.cghjournal.org/article/S1542-3565(15)00158-5/pdf. DISCLAIMER: I have no medical or scientific training. I just like making cute cartoon videos about the power of plants. IMPORTANT: This video is not intended as medical advice. Always consult your doctor for medical advice. Never make any changes to your diet or medications without first consulting your doctor.
Просмотров: 68 Big Broccoli
Rectal route - foam enema
Просмотров: 113910 Fran Jones
Crohn's Talk 2 Prednisone Face
Taking prednisone changed my outward appearance but not me. It was a miracle drug but tough to quit.
Просмотров: 97 Marcus Williams
Ulcerative Colitis: Steroids, Medication & Advice
Hello everyone :) Hope you're all well. This video is just the 'journey so far' of my colitis and how I've been managing medication I've been put on and also any side effects I've had. Not to scare anyone or be seen as 'indulgent' but hopefully to help. HELLO MOON FACE! Although the idea of steroids can be scary what they do is amazing. I feel totally different. If you have any real questions to do with the drugs ask your doctor until you feel perfectly happy. I'm just here for if you have any little worrys that hopefully I could help you with :) I have two weeks left on the steroid medication and still on the same doseage of Asacol. Where to find me if you want to talk; https://twitter.com/hann8h http://hann8h.tumblr.com/ Instagram: @hann8h Be strong xx
Просмотров: 2311 Hannah Grace
Generic Drug Prices are Going Up. In Some Cases, Way Up.
Get more medical news analysis at http://www.medpagetoday.com or http://www.methodsman.com Want a great investment vehicle? How about this – if you used $10,000 to buy 3000 Mesalamine enemas in 2008, you could sell them today for $380,000. Sure – your garage would look a bit strange, but you can't blink at that return. Prescription drug prices are a frustrating little chunk of the economy that cause no end of strife to patients and doctors, and even the occasional politician. But generic drugs – they aren't a problem, right? As Obi-Wan Kenobi so aptly put it, speaking, I think, of generic drugs: "You were the chosen one". But a new study, appearing in the Annals of Internal Medicine shows us that some generic drug prices have been increasing. And, more interestingly, it begins to suggest why. Researchers from Harvard and the University of Florida pulled data from over 1 billion prescriptions to figure out what patients and insurers were paying for generic drugs from 2008 to 2013. That billion prescriptions represented just over 1000 medications, whose prices were individually tracked. But what gives this study its real kick is that they determined how much competition was in the market – in other words – how many generic manufacturers were making the drug. Want to take bets on how this worked out? The average drug increased in price by 30% over the study period. But be careful, this is complicated. Some of those 1000 drugs have almost no market. The average cost of a prescription went down by 14% over that period. This is not necessarily good news. Even if the average generic prescription cost went down, the spread was huge. Some drug prices increased a lot. What drove that increase? In short, lack of competition. The fewer manufacturers of a generic there were, the faster the price of that generic rose. This was true regardless of the starting price of the drug, though drugs that started off cheaper tended to grow faster. What you see in this graph is pretty clear. Generic prices go up more when there are fewer producers of the generic. Econ 101 stuff. By the way, just under half of the drugs were in a duopoly or less competitive situation. There are some fixes here. The Office of Generic Drugs now grants expedited review to generics entering a market where there is currently a monopoly present. But they do not expedite review of drugs trying to break into a duopoly or other less-than-competitive situations. Reducing regulations is a nice conservative principle that would probably increase competition and bring costs down. On the liberal side, we could also allow importation of generics from places like Canada to keep prices competitive. Isn't it nice when both sides can agree on an issue? Given the data laid out here, I'm sure we'll have a bipartisan drug-price-reducing bill on the president's desk any day now.
Просмотров: 49 F. Perry Wilson
Ulcerative Colitis Remission 4 Tips For Staying In UC Remission!!
In this video, I'm going to talk about some of the keys to stay in remission. Now, colitis is such a tricky disease because we go through this ebb and flow of getting in remission feeling great then feeling debilitating, going to the bathroom, living in the bathroom, and having your life just be in the bathroom. Visit My Website: erinleighhealth.com As far as what's going to trigger your disease, a family event, a life event can happen, which can put you back into a flare. It is a delicate balance between wanting to have a life that you want to live, and also keeping your health in check. My video is really about some of the things that could help you stay in remission. I know I've made so many mistakes. And I still do with this disease. I just wanted to share some things with you that are important because it might not feel like you should be taking medication or you have to see doctors and stuff like that. I wanted to give you some perspective today on keys on staying into in remission, or if you're new, just kind of some tips and tricks Stay on medication I’m basically a maintenance drug for ever called Apriso. Some studies that have shown mesalamine actually prevents from colon cancer. Luckily this medication has little to no side effects for me. Stay on your medication, even though you feel great is the key. So going off medication, there's been times where I've not taking my medication and for longer periods of time thinking I'm good and then it just resulted in me going to a flare. Read more about the study behind ulcerative colitis and remission! https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014050/ Keep Doctor Visits Keep up with your doctor's visits. Make sure you're always having appointments every six months and have a really good relationship with your doctor.Find a support system that you can turn to and a doctor that you can trust. Eat A Healthy Diet The third thing is make sure that you are eating a healthy diet. Now, I'm not going to go too much into this right now because it's such a long explanation. But different foods trigger different symptoms and some people do really well on certain diets with this disease. It just really depends. So if you're first diagnosed, I would definitely audit your diet. Start with either elimination diet or SCD diet (Specific Carbohydrate Diet) and I'll probably do some videos on those. You want to make sure that you are understanding what foods trigger you make you feel bloated, crappy, just not good at all. Sleep So the next thing is getting enough sleep. I know I don't do it. Often. I have two little ones. So I don't do it. But what I do make up for is my sleep and my stress. Cortisol has such an impact your health that you just have to keep it in check. Sometimes it's not realistic. Stress The next one is just keeping your stress level slow. Figure out what things that stress you out if you have a stressful job. If you can't handle the stress, if you can't find a coping mechanism, you need to try to do that. Because so incredibly important. Like I said, on one of my other videos, I am so incredibly scared of talking in public, so I had to overcome that.
Просмотров: 28 Erin Leigh
Mesalazine and thymoquinone attenuate intestinal tumour development in Msh2loxP/loxP Villin-Cre mice
Read the paper here: http://gut.bmj.com/content/early/2014/11/26/gutjnl-2014-307663 Kortüm M, Campregher C, Lang M et al. Gut 2015: doi:10.1136/gutjnl-2014-307663 Objective Lynch syndrome is caused by germline mutations in DNA mismatch repair genes leading to microsatellite instability and colorectal cancer. Mesalazine, commonly used for the treatment of UC, reduces MSI in vitro. Here, we tested natural compounds for such activity and applied mesalazine and thymoquinone in a Msh2loxP/loxP Villin-Cre mouse model for Lynch syndrome. Design Flow cytometry was used for quantitation of mutation rates at a CA13 microsatellite in human colon cancer cells that had been stably transfected with pIREShyg2-enhanced green fluorescent protein/CA13, a reporter for frameshift mutations. Mice were treated for 43 weeks with mesalazine, thymoquinone or control chow. Intestines were analysed for tumour incidence, tumour multiplicity and size. MSI testing was performed from microdissected normal intestinal or tumour tissue, compared with mouse tails and quantified by the number of mutations per marker. Results Besides mesalazine, thymoquinone significantly improved replication fidelity at 1.25 and 2.5 µM in HCT116 cells. In Msh2loxP/loxP Villin-Cre mice, tumour incidence was reduced by mesalazine from 94% to 69% and to 56% by thymoquinone. The mean number of tumours was reduced from 3.1 to 1.4 by mesalazineand to 1.1 by thymoquinone. Interestingly, MSI was reduced in normal intestinal tissue from 1.5 to 1.2 NMPM and to 1.1 NMPM by mesalazine and thymoquinone, respectively. Thymoquinone, but not mesalazine, reduced MSI in tumours. Conclusions Mesalazine and thymoquinone reduce tumour incidence and multiplicity in Msh2loxP/loxP Villin-Cre mice by reduction of MSI independent of a functional mismatch repair system. Both substances are candidate compounds for chemoprevention in Lynch syndrome mutation carriers.
Просмотров: 1974 Gut
How to use liquid enemas
This video has been adapted from a DVD, the contents of which was written by Dr Andrew Robinson and IBD specialist nurse Cath Stansfield. The DVD was produced following an unrestricted educational grant from Falk Pharma.
Просмотров: 141215 HELPWITHIBD
Rectal route - liquid enema
Просмотров: 127521 Fran Jones
Apriso - Conversation with Pascal Ober
Просмотров: 553 ManagingAutomation
How to use Suppository
Animated Video created using Animaker - http://www.animaker.com suppository
Просмотров: 267601 RaiZoGo
How to use a suppository.m4v
This video will teach you how to remove a suppository from the most common molds that we use at the pharmacy and explain how storage and insertion techniques. For more question please call the Medicine Shoppe Pharmacy in New Philadelphia, Ohio at 830-1028. The Medicine Shoppe is an accredited compounding pharmacy by PCAB.
Просмотров: 122078 gomedshoprx
Enema Administration
Просмотров: 454151 Suzymb66
Rectal suppository administration
Просмотров: 400178 Suzymb66